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New eight genes identified at the clinical multidrug-resistant Acinetobacter baumannii DMS06669 strain in a Vietnam hospital

Overview of attention for article published in Annals of Clinical Microbiology and Antimicrobials, November 2017
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Title
New eight genes identified at the clinical multidrug-resistant Acinetobacter baumannii DMS06669 strain in a Vietnam hospital
Published in
Annals of Clinical Microbiology and Antimicrobials, November 2017
DOI 10.1186/s12941-017-0250-9
Pubmed ID
Authors

Nguyen Si-Tuan, Hua My Ngoc, Pham Thi Thu Hang, Cuong Nguyen, Pham Hung Van, Nguyen Thuy Huong

Abstract

Acinetobacter baumannii is an important nosocomial pathogen that can develop multidrug resistance. In this study, we characterized the genome of the A. baumannii strain DMS06669 (isolated from the sputum of a male patient with hospital-acquired pneumonia) and focused on identification of genes relevant to antibiotic resistance. Whole genome analysis of A. baumannii DMS06669 from hospital-acquired pneumonia patients included de novo assembly; gene prediction; functional annotation to public databases; phylogenetics tree construction and antibiotics genes identification. After sequencing the A. baumannii DMS06669 genome and performing quality control, de novo genome assembly was carried out, producing 24 scaffolds. Public databases were used for gene prediction and functional annotation to construct a phylogenetic tree of the DMS06669 strain with 21 other A. baumannii strains. A total of 18 possible antibiotic resistance genes, conferring resistance to eight distinct classes of antibiotics, were identified. Eight of these genes have not previously been reported to occur in A. baumannii. Our results provide important information regarding mechanisms that may contribute to antibiotic resistance in the DMS06669 strain, and have implications for treatment of patients infected with A. baumannii.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 56 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 14%
Student > Ph. D. Student 7 13%
Researcher 6 11%
Other 5 9%
Student > Postgraduate 4 7%
Other 6 11%
Unknown 20 36%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 14 25%
Medicine and Dentistry 5 9%
Immunology and Microbiology 4 7%
Agricultural and Biological Sciences 3 5%
Veterinary Science and Veterinary Medicine 2 4%
Other 6 11%
Unknown 22 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 November 2017.
All research outputs
#13,881,544
of 23,008,860 outputs
Outputs from Annals of Clinical Microbiology and Antimicrobials
#259
of 611 outputs
Outputs of similar age
#170,214
of 325,276 outputs
Outputs of similar age from Annals of Clinical Microbiology and Antimicrobials
#5
of 11 outputs
Altmetric has tracked 23,008,860 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 611 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 325,276 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.