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Mendeley readers
| Title |
Targeting cholesterol synthesis increases chemoimmuno-sensitivity in chronic lymphocytic leukemia cells
|
|---|---|
| Published in |
Experimental Hematology & Oncology, September 2014
|
| DOI | 10.1186/2162-3619-3-24 |
| Pubmed ID | |
| Authors |
Indira Benakanakere, Tyler Johnson, Richard Sleightholm, Virgilio Villeda, Monika Arya, Ravi Bobba, Carl Freter, Chunfa Huang |
| Abstract |
Cholesterol plays an important role in cancer development, drug resistance and chemoimmuno-sensitivity. Statins, cholesterol lowering drugs, can induce apoptosis, but also negatively interfere with CD-20 and rituximab-mediated activity. Our goal is to identify the alternative targets that could reduce cholesterol levels but do not interfere with CD-20 in chemo immunotherapy of chronic lymphocytic leukemia (CLL). |
Mendeley readers
The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 22 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 5 | 23% |
| Other | 4 | 18% |
| Student > Bachelor | 4 | 18% |
| Student > Ph. D. Student | 3 | 14% |
| Professor | 1 | 5% |
| Other | 2 | 9% |
| Unknown | 3 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 6 | 27% |
| Medicine and Dentistry | 5 | 23% |
| Agricultural and Biological Sciences | 3 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 9% |
| Chemical Engineering | 1 | 5% |
| Other | 1 | 5% |
| Unknown | 4 | 18% |