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Effectiveness and cost of quick diagnostic tests to determine tetanus immunity in patients with a wound in french emergency departments

Overview of attention for article published in BMC Infectious Diseases, November 2014
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Title
Effectiveness and cost of quick diagnostic tests to determine tetanus immunity in patients with a wound in french emergency departments
Published in
BMC Infectious Diseases, November 2014
DOI 10.1186/s12879-014-0603-3
Pubmed ID
Authors

Dieynaba S N'Diaye, Michaël Schwarzinger, Dorothée Obach, Julien Poissy, Sophie Matheron, Enrique Casalino, Yazdan Yazdanpanah

Abstract

BackgroundTétanos Quick Stick® (TQS) is a test for tetanus immunity screening for wounded patients in emergency departments (EDs), but represents additional costs compared with a medical interview on vaccination history. The study objective was to assess the effectiveness and cost of the TQS in French EDs.MethodsWe performed a model-based analysis that simulates screening of tetanus immunity and risk of tetanus based on prophylaxis administration. Strategies compared were: i) diagnosis of tetanus immunity by ¿TQS¿; ii) ¿Medical Interview¿ (current practice). The study population was 1,658,000 French adults seeking ED care for a wound in 2012. Model parameters were estimated based on French national surveillance data, and published literature. Outcome measures were number of tetanus cases, life years gained and costs (2012 ¿) from a societal perspective.ResultsUse of TQS had negligible impact on health outcomes (0.02 tetanus cases/year in France vs. 0.41 for ¿Medical Interview¿), but resulted in a decrease in annual costs of ¿2,203,000 (¿42%). Base case and sub-group analysis showed that with the same effectiveness, the average cost per patient was: ¿13 with ¿Medical Interview¿ vs. ¿11.7 with TQS for the overall cohort; ¿28.9 with ¿Medical Interview¿ vs. ¿21 with ¿TQS¿ for tetanus-prone wounds; ¿15 with ¿Medical Interview¿ vs. ¿14.1 with ¿TQS¿ for patients aged ¿65 years; and ¿6.2 with ¿Medical Interview¿ vs. ¿7.8 with ¿TQS¿ for non-tetanus-prone wounds.ConclusionsUse of TQS is as effective and less costly than ¿Medical Interview¿ when applied in ED to wounded patients with tetanus-prone wounds or aged ¿65 years. However, it is more expensive in patients with non-tetanus-prone wounds.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 17%
Student > Bachelor 4 13%
Student > Ph. D. Student 3 10%
Other 2 7%
Student > Doctoral Student 2 7%
Other 4 13%
Unknown 10 33%
Readers by discipline Count As %
Medicine and Dentistry 6 20%
Nursing and Health Professions 2 7%
Agricultural and Biological Sciences 1 3%
Economics, Econometrics and Finance 1 3%
Psychology 1 3%
Other 5 17%
Unknown 14 47%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 November 2014.
All research outputs
#17,732,540
of 22,771,140 outputs
Outputs from BMC Infectious Diseases
#5,092
of 7,668 outputs
Outputs of similar age
#248,140
of 362,502 outputs
Outputs of similar age from BMC Infectious Diseases
#119
of 196 outputs
Altmetric has tracked 22,771,140 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,668 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 362,502 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 196 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.