Title |
Performance of TB immunodiagnostic tests in Eurasian badgers (Meles meles) of different ages and the influence of duration of infection on serological sensitivity
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Published in |
BMC Veterinary Research, November 2009
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DOI | 10.1186/1746-6148-5-42 |
Pubmed ID | |
Authors |
Mark A Chambers, Sue Waterhouse, Konstantin Lyashchenko, Richard Delahay, Robin Sayers, R Glyn Hewinson |
Abstract |
In parts of Great Britain and Ireland, Eurasian badgers (Meles meles) constitute a reservoir of Mycobacterium bovis infection and a potential source of infection for cattle. In vitro diagnostic tests for live badgers are an important component of strategies to control TB in this species. Immunological tests have been developed for badgers, although little is known about the influence of the age of the animal on test performance. To address this, we evaluated the performance of three immunological tests for badgers with respect to the age of the animal: the Brock Test and BrockTB STAT-PAK serological tests and the recently developed interferon-gamma enzyme immunoassay (IFNgamma EIA). Data published elsewhere suggested that seropositivity was associated with more progressive forms of TB in the badger. To gain further evidence for this, we used longitudinal data from a well-studied population of badgers to test for an association between the sensitivity of the Brock Test and the duration of TB infection. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 6 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 6 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 3 | 2% |
India | 2 | 1% |
United Arab Emirates | 1 | <1% |
Turkey | 1 | <1% |
Colombia | 1 | <1% |
Portugal | 1 | <1% |
United Kingdom | 1 | <1% |
Iran, Islamic Republic of | 1 | <1% |
Japan | 1 | <1% |
Other | 0 | 0% |
Unknown | 133 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 32 | 22% |
Researcher | 28 | 19% |
Student > Master | 22 | 15% |
Student > Bachelor | 12 | 8% |
Professor > Associate Professor | 10 | 7% |
Other | 26 | 18% |
Unknown | 15 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 76 | 52% |
Environmental Science | 25 | 17% |
Medicine and Dentistry | 7 | 5% |
Veterinary Science and Veterinary Medicine | 5 | 3% |
Social Sciences | 3 | 2% |
Other | 8 | 6% |
Unknown | 21 | 14% |