You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Differential biologic effects of CPD and 6-4PP UV-induced DNA damage on the induction of apoptosis and cell-cycle arrest
|
|---|---|
| Published in |
BMC Cancer, October 2005
|
| DOI | 10.1186/1471-2407-5-135 |
| Pubmed ID | |
| Authors |
Hsin-Lung Lo, Satoshi Nakajima, Lisa Ma, Barbara Walter, Akira Yasui, Douglas W Ethell, Laurie B Owen |
| Abstract |
UV-induced damage can induce apoptosis or trigger DNA repair mechanisms. Minor DNA damage is thought to halt the cell cycle to allow effective repair, while more severe damage can induce an apoptotic program. Of the two major types of UV-induced DNA lesions, it has been reported that repair of CPD, but not 6-4PP, abrogates mutation. To address whether the two major forms of UV-induced DNA damage, can induce differential biological effects, NER-deficient cells containing either CPD photolyase or 6-4 PP photolyase were exposed to UV and examined for alterations in cell cycle and apoptosis. In addition, pTpT, a molecular mimic of CPD was tested in vitro and in vivo for the ability to induce cell death and cell cycle alterations. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 163 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| India | 2 | 1% |
| United Kingdom | 1 | <1% |
| Unknown | 158 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 36 | 22% |
| Student > Master | 26 | 16% |
| Researcher | 23 | 14% |
| Student > Bachelor | 22 | 13% |
| Student > Doctoral Student | 7 | 4% |
| Other | 16 | 10% |
| Unknown | 33 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 50 | 31% |
| Biochemistry, Genetics and Molecular Biology | 37 | 23% |
| Medicine and Dentistry | 12 | 7% |
| Chemistry | 11 | 7% |
| Unspecified | 3 | 2% |
| Other | 14 | 9% |
| Unknown | 36 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 November 2014.
All research outputs
#18,384,336
of 22,771,140 outputs
Outputs from BMC Cancer
#5,416
of 8,281 outputs
Outputs of similar age
#55,433
of 58,977 outputs
Outputs of similar age from BMC Cancer
#8
of 9 outputs
Altmetric has tracked 22,771,140 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,281 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 58,977 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 3rd percentile – i.e., 3% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one.