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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Chloride-liberal fluids are associated with acute kidney injury after liver transplantation
|
|---|---|
| Published in |
Critical Care, November 2014
|
| DOI | 10.1186/s13054-014-0625-7 |
| Pubmed ID | |
| Authors |
Ashraf Nadeem, Nawal Salahuddin, Alyaa El Hazmi, Mini Joseph, Balsam Bohlega, Hend Sallam, Yasser Sheikh, Dieter Broering |
| Abstract |
IntroductionAcute Kidney Injury (AKI) occurs frequently after liver transplantation and is associated with significant morbidity and mortality. Recent evidence has linked the predominant usage of `chloride-liberal¿ intravenous fluids, such as 0.9% saline to the development of renal dysfunction in general critically ill patients. We compared the effects of perioperative fluid types on AKI in liver transplant recipients.MethodsAn observational analysis of liver transplant recipients over a 33-month period, between January 2010 to September 2013, was performed. Intensive care unit database and patient records were analyzed for determinants of early postoperative AKI. Univariate and multivariate regression analysis was carried out using a two-tailed p value less than 0.05 to establish significance. The institutional Research Ethics Committee approved the study methodology (RAC no.2131 073).ResultsOne hundred fifty-eight liver transplants were performed, AKI developed in 57 (36.1%) patients; 39 (68.4%) fully recovered, 13 (22.8%) developed chronic renal failure and 10 (17.5%) required long-term hemodialysis. On univariate regression analysis, AKI was significantly associated with greater than 3200 ml of chloride-liberal fluids infused within the first post-operative day (HR 5.9, 95% CI 2.64, 13.2, P <0.001), greater than 1500 ml colloids received in the operating room (hazard ratio (HR) 1.97, 95% CI 1.01, 3.8, P =0.046), vasopressor requirement for 48 hours post-transplant (HR 3.34, 95% CI 1.55, 7.21, P =0.002), hyperchloremia at day 2 (HR 1.09, 95% CI 1.01, 1.18, P =0.015) and preoperative model for endstage liver disease (MELD) score (HR 1.08, 95% CI 1.03, 1.13, P <0.001).After stepwise multivariate regression, infusion of greater than 3200 ml of chloride-liberal fluids (HR 6.25, 95% CI 2.69, 14.5, P <0.000) and preoperative MELD score (HR 1.08, 95% CI 1.02, 1.15, P =0.004) remained significant predictors for AKI.ConclusionsIn a sample of liver transplant recipients, infusion of higher volumes of chloride-liberal fluids and preoperative status was associated with an increased risk for post-operative AKI. |
X Demographics
The data shown below were collected from the profiles of 21 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Saudi Arabia | 5 | 24% |
| United States | 2 | 10% |
| United Kingdom | 2 | 10% |
| Australia | 2 | 10% |
| Canada | 2 | 10% |
| Spain | 1 | 5% |
| Colombia | 1 | 5% |
| Greece | 1 | 5% |
| India | 1 | 5% |
| Other | 0 | 0% |
| Unknown | 4 | 19% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 43% |
| Practitioners (doctors, other healthcare professionals) | 8 | 38% |
| Science communicators (journalists, bloggers, editors) | 2 | 10% |
| Scientists | 1 | 5% |
| Unknown | 1 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 2 | 2% |
| Mexico | 1 | 1% |
| United States | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 82 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 13 | 15% |
| Student > Master | 12 | 14% |
| Researcher | 9 | 10% |
| Student > Ph. D. Student | 9 | 10% |
| Student > Doctoral Student | 7 | 8% |
| Other | 28 | 32% |
| Unknown | 9 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 60 | 69% |
| Nursing and Health Professions | 5 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Earth and Planetary Sciences | 2 | 2% |
| Computer Science | 1 | 1% |
| Other | 2 | 2% |
| Unknown | 15 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 March 2016.
All research outputs
#2,596,743
of 25,715,849 outputs
Outputs from Critical Care
#2,230
of 6,605 outputs
Outputs of similar age
#34,374
of 371,937 outputs
Outputs of similar age from Critical Care
#31
of 166 outputs
Altmetric has tracked 25,715,849 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,605 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.7. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 371,937 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 166 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.