Title |
Characterization of the Vitrocell® 24/48 in vitroaerosol exposure system using mainstream cigarette smoke
|
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Published in |
BMC Chemistry, November 2014
|
DOI | 10.1186/s13065-014-0062-3 |
Pubmed ID | |
Authors |
Shoaib Majeed, Stefan Frentzel, Sandra Wagner, Diana Kuehn, Patrice Leroy, Philippe A Guy, Arno Knorr, Julia Hoeng, Manuel C Peitsch |
Abstract |
Only a few exposure systems are presently available that enable cigarette smoke exposure of living cells at the air-liquid interface, of which one of the most versatile is the Vitrocell® system (Vitrocell® Systems GmbH). To assess its performance and optimize the exposure conditions, we characterized a Vitrocell® 24/48 system connected to a 30-port carousel smoking machine. The Vitrocell® 24/48 system allows for simultaneous exposure of 48 cell culture inserts using dilution airflow rates of 0-3.0 L/min and exposes six inserts per dilution. These flow rates represent cigarette smoke concentrations of 7-100%. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Germany | 1 | 6% |
Unknown | 16 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Doctoral Student | 3 | 18% |
Student > Bachelor | 3 | 18% |
Researcher | 3 | 18% |
Student > Ph. D. Student | 3 | 18% |
Professor | 1 | 6% |
Other | 2 | 12% |
Unknown | 2 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Engineering | 4 | 24% |
Biochemistry, Genetics and Molecular Biology | 3 | 18% |
Agricultural and Biological Sciences | 3 | 18% |
Chemistry | 3 | 18% |
Environmental Science | 1 | 6% |
Other | 1 | 6% |
Unknown | 2 | 12% |