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Array comparative genomic hybridization analyses of all blastomeres of a cohort of embryos from young IVF patients revealed significant contribution of mitotic errors to embryo mosaicism at the…

Overview of attention for article published in Reproductive Biology and Endocrinology, November 2014
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Title
Array comparative genomic hybridization analyses of all blastomeres of a cohort of embryos from young IVF patients revealed significant contribution of mitotic errors to embryo mosaicism at the cleavage stage
Published in
Reproductive Biology and Endocrinology, November 2014
DOI 10.1186/1477-7827-12-105
Pubmed ID
Authors

Judy FC Chow, William SB Yeung, Estella YL Lau, Vivian CY Lee, Ernest HY Ng, Pak-Chung Ho

Abstract

Embryos produced by in vitro fertilization (IVF) have a high level of aneuploidy, which is believed to be a major factor affecting the success of human assisted reproduction treatment. The aneuploidy rate of cleavage stage embryos based on 1-2 biopsied blastomeres has been well-reported, however, the true aneuploidy rate of whole embryos remain unclear because of embryo mosaicism. To study the prevalence of mosaicism in top quality IVF embryos, surplus embryos donated from young patients (aged 28-32) in the assisted reproduction program at Queen Mary Hospital, Hong Kong were used.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 53 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 17%
Student > Ph. D. Student 8 15%
Student > Bachelor 7 13%
Researcher 7 13%
Other 3 6%
Other 6 11%
Unknown 13 25%
Readers by discipline Count As %
Medicine and Dentistry 14 26%
Agricultural and Biological Sciences 12 23%
Biochemistry, Genetics and Molecular Biology 11 21%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Nursing and Health Professions 1 2%
Other 3 6%
Unknown 10 19%