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Molecular evidence for increased regulatory conservation during metamorphosis, and against deleterious cascading effects of hybrid breakdown in Drosophila

Overview of attention for article published in BMC Biology, March 2010
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Title
Molecular evidence for increased regulatory conservation during metamorphosis, and against deleterious cascading effects of hybrid breakdown in Drosophila
Published in
BMC Biology, March 2010
DOI 10.1186/1741-7007-8-26
Pubmed ID
Authors

Carlo G Artieri, Rama S Singh

Abstract

Speculation regarding the importance of changes in gene regulation in determining major phylogenetic patterns continues to accrue, despite a lack of broad-scale comparative studies examining how patterns of gene expression vary during development. Comparative transcriptional profiling of adult interspecific hybrids and their parental species has uncovered widespread divergence of the mechanisms controlling gene regulation, revealing incompatibilities that are masked in comparisons between the pure species. However, this has prompted the suggestion that misexpression in adult hybrids results from the downstream cascading effects of a subset of genes improperly regulated in early development.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 8%
United Kingdom 1 4%
Spain 1 4%
Sweden 1 4%
Unknown 21 81%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 35%
Researcher 4 15%
Student > Master 3 12%
Professor 2 8%
Other 2 8%
Other 2 8%
Unknown 4 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 58%
Biochemistry, Genetics and Molecular Biology 4 15%
Computer Science 2 8%
Medicine and Dentistry 1 4%
Unknown 4 15%