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Association of HbA1c with hospitalization and mortality among patients with heart failure and diabetes

Overview of attention for article published in BMC Cardiovascular Disorders, May 2016
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Title
Association of HbA1c with hospitalization and mortality among patients with heart failure and diabetes
Published in
BMC Cardiovascular Disorders, May 2016
DOI 10.1186/s12872-016-0275-6
Pubmed ID
Authors

Saul Blecker, Hannah Park, Stuart D. Katz

Abstract

Comorbid diabetes is common in heart failure and associated with increased hospitalization and mortality. Nonetheless, the association between glycemic control and outcomes among patients with heart failure and diabetes remains poorly characterized, particularly among low income and minority patients. We performed a retrospective cohort study of outpatients with heart failure and diabetes in the New York City Health and Hospitals Corporation, the largest municipal health care system in the United States. Cox proportional hazard models were used to measure the association between HbA1c levels and outcomes of all-cause hospitalization, heart failure hospitalization, and mortality. Of 4723 patients with heart failure and diabetes, 42.6 % were black, 30.5 % were Hispanic/Latino, 31.4 % were Medicaid beneficiaries and 22.9 % were uninsured. As compared to patients with an HbA1c of 8.0-8.9 %, patients with an HbA1c of <6.5, 6.5-6.9, 7.0-7.9, and ≥9.0 % had an adjusted hazard ratio (aHR) (95 % CI) for all-cause hospitalization of 1.03 (0.90-1.17), 1.05 (0.91-1.22), 1.03 (0.90-1.17), and 1.13 (1.00-1.28), respectively. An HbA1c ≥ 9.0 % was also associated with an increased risk of heart failure hospitalization (aHR 1.33; 95 % CI 1.11-1.59) and a non-significant increased risk in mortality (aHR 1.20; 95 % CI 0.99-1.45) when compared to HbA1c of 8.0-8.9 %. Among a cohort of primarily minority and low income patients with heart failure and diabetes, an increased risk of hospitalization was observed only for an HbA1c greater than 9 %.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 53 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 15%
Student > Bachelor 7 13%
Student > Ph. D. Student 5 9%
Other 4 8%
Student > Postgraduate 3 6%
Other 7 13%
Unknown 19 36%
Readers by discipline Count As %
Medicine and Dentistry 18 34%
Nursing and Health Professions 4 8%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Biochemistry, Genetics and Molecular Biology 1 2%
Computer Science 1 2%
Other 3 6%
Unknown 24 45%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2017.
All research outputs
#18,576,855
of 23,008,860 outputs
Outputs from BMC Cardiovascular Disorders
#1,127
of 1,637 outputs
Outputs of similar age
#250,896
of 333,920 outputs
Outputs of similar age from BMC Cardiovascular Disorders
#23
of 34 outputs
Altmetric has tracked 23,008,860 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,637 research outputs from this source. They receive a mean Attention Score of 3.9. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 333,920 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.