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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Drug resistance genomics of the antimalarial drug artemisinin
|
|---|---|
| Published in |
Genome Biology, November 2014
|
| DOI | 10.1186/s13059-014-0544-6 |
| Pubmed ID | |
| Authors |
Elizabeth A Winzeler, Micah J Manary |
| Abstract |
Across the globe, over 200 million annual malaria infections result in up to 660,000 deaths, 77% of which occur in children under the age of five years. Although prevention is important, malaria deaths are typically prevented by using antimalarial drugs that eliminate symptoms and clear parasites from the blood. Artemisinins are one of the few remaining compound classes that can be used to cure multidrug-resistant Plasmodium falciparum infections. Unfortunately, clinical trials from Southeast Asia are showing that artemisinin-based treatments are beginning to lose their effectiveness, adding renewed urgency to the search for the genetic determinants of parasite resistance to this important drug class. We review the genetic and genomic approaches that have led to an improved understanding of artemisinin resistance, including the identification of resistance-conferring mutations in the P. falciparum kelch13 gene. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 17% |
| United Kingdom | 1 | 17% |
| Jordan | 1 | 17% |
| Colombia | 1 | 17% |
| Unknown | 2 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Science communicators (journalists, bloggers, editors) | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 281 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | <1% |
| United States | 2 | <1% |
| Vietnam | 1 | <1% |
| Ghana | 1 | <1% |
| Brazil | 1 | <1% |
| Burkina Faso | 1 | <1% |
| Taiwan | 1 | <1% |
| Senegal | 1 | <1% |
| Unknown | 271 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 59 | 21% |
| Student > Ph. D. Student | 47 | 17% |
| Researcher | 44 | 16% |
| Student > Bachelor | 28 | 10% |
| Student > Postgraduate | 18 | 6% |
| Other | 48 | 17% |
| Unknown | 37 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 73 | 26% |
| Biochemistry, Genetics and Molecular Biology | 66 | 23% |
| Medicine and Dentistry | 27 | 10% |
| Chemistry | 24 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 18 | 6% |
| Other | 28 | 10% |
| Unknown | 45 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2023.
All research outputs
#1,858,478
of 25,374,647 outputs
Outputs from Genome Biology
#1,547
of 4,467 outputs
Outputs of similar age
#24,748
of 369,552 outputs
Outputs of similar age from Genome Biology
#35
of 99 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 369,552 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 99 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.