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Characteristics of Dorsal Root Ganglia Neurons Sensitive to Substance P

Overview of attention for article published in Molecular Pain, January 2014
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Title
Characteristics of Dorsal Root Ganglia Neurons Sensitive to Substance P
Published in
Molecular Pain, January 2014
DOI 10.1186/1744-8069-10-73
Pubmed ID
Authors

Eder Ricardo Moraes, Christopher Kushmerick, Ligia Araujo Naves

Abstract

Substance P modulates ion channels and the excitability of sensory neurons in pain pathways. Within the heterogeneous population of Dorsal Root Ganglia (DRG) primary sensory neurons, the properties of cells that are sensitive to Substance P are poorly characterized. To define this population better, dissociated rat DRG neurons were tested for their responsiveness to capsaicin, ATP and acid. Responses to ATP were classified according to the kinetics of current activation and desensitization. The same cells were then tested for modulation of action potential firing by Substance P.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 45 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 38%
Researcher 7 16%
Other 3 7%
Student > Master 3 7%
Professor 2 4%
Other 8 18%
Unknown 5 11%
Readers by discipline Count As %
Neuroscience 10 22%
Agricultural and Biological Sciences 8 18%
Biochemistry, Genetics and Molecular Biology 6 13%
Medicine and Dentistry 6 13%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 6 13%
Unknown 7 16%