Title |
A novel pathogenic classification of cancers
|
---|---|
Published in |
Cancer Cell International, November 2014
|
DOI | 10.1186/s12935-014-0113-9 |
Pubmed ID | |
Authors |
Carlos Sonnenschein, Barbara Davis, Ana M Soto |
Abstract |
According to contemporary epidemiological and experimental evidence, we propose a novel classification of cancers based on pathogenesis instead of classifications based on histological appearance of cancer. This new scheme first defines cancers as either 1. inborn errors of development or 2. sporadic ones, and then sub-defines the former into 1A. inborn inherited errors of development, being those due to mutations contributed by one or both parents' gametes to the developing conceptus, and 1B. inborn induced errors of development when the malformations and/or cancers are due to environmental carcinogenic exposure during pregnancy. It is anticipated that the origin of an increasing number of so-called sporadic cancers will turn out to be linked to the inborn induced errors of development group. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Italy | 1 | 3% |
Unknown | 35 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 5 | 14% |
Other | 5 | 14% |
Researcher | 5 | 14% |
Student > Bachelor | 3 | 8% |
Professor | 2 | 6% |
Other | 5 | 14% |
Unknown | 11 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 14% |
Agricultural and Biological Sciences | 4 | 11% |
Biochemistry, Genetics and Molecular Biology | 4 | 11% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Mathematics | 1 | 3% |
Other | 5 | 14% |
Unknown | 16 | 44% |