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X Demographics
Mendeley readers
Attention Score in Context
| Title |
In vitro antimicrobial, antioxidant and cytotoxic properties of Streptomyces lavendulae strain SCA5
|
|---|---|
| Published in |
BMC Microbiology, November 2014
|
| DOI | 10.1186/s12866-014-0291-6 |
| Pubmed ID | |
| Authors |
Pachaiyappan Saravana Kumar, Naif Abdullah Al-Dhabi, Veeramuthu Duraipandiyan, Chandrasekar Balachandran, Panthagani Praveen Kumar, Savarimuthu Ignacimuthu |
| Abstract |
BackgroundActinomycetes are Gram-positive, often filamentous, bacteria known for their unsurpassed capacity for the production of secondary metabolites with diverse biological activities. The aim of the present study was to evaluate the antimicrobial, cytotoxic and antioxidant properties of Streptomyces lavendulae strain SCA5.ResultsThe ethyl acetate extract of SCA5 broth (EA-SCA5) showed antimicrobial activity with MIC value of 31.25 ¿g/ml. EA-SCA5 showed good antioxidant potential by scavenging 2, 2-diphenyl-picrylhydrazyl (DPPH) (IC50 507.61¿±¿0.66 ¿g/ml), hydroxyl radical (IC50 617.84¿±¿0.57 ¿g/ml), nitric oxide (IC50 730.92¿±¿0.81 ¿g/ml) and superoxide anion radical (IC50 864.71¿±¿1.15 ¿g/ml). The EA-SCA5 also showed strong suppressive effect on rat liver lipid peroxidation (IC50 838.83¿±¿1.18 ¿g/ml). The total phenolic content of SCA5 was 577.12 mg of GAE equivalents/gram extract. EA-SCA5 exhibited cytotoxic activity on A549 adenocarcinoma lung cancer cell line. It showed 84.9% activity at 500 ¿g/ml with IC50 value of 200 ¿g/ml. The gas chromatography mass spectrometry (GC-MS) analysis revealed the presence of one major bioactive compound actinomycin C2.ConclusionsThe results of this study indicate that the EA-SCA5 could be probed further for isolating some medically useful compounds. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 1% |
| Unknown | 88 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 16% |
| Researcher | 13 | 15% |
| Student > Master | 11 | 12% |
| Student > Doctoral Student | 9 | 10% |
| Student > Bachelor | 8 | 9% |
| Other | 12 | 13% |
| Unknown | 22 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 19 | 21% |
| Biochemistry, Genetics and Molecular Biology | 16 | 18% |
| Immunology and Microbiology | 10 | 11% |
| Medicine and Dentistry | 5 | 6% |
| Environmental Science | 3 | 3% |
| Other | 9 | 10% |
| Unknown | 27 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 August 2023.
All research outputs
#2,633,395
of 24,205,409 outputs
Outputs from BMC Microbiology
#185
of 3,330 outputs
Outputs of similar age
#37,414
of 370,152 outputs
Outputs of similar age from BMC Microbiology
#1
of 59 outputs
Altmetric has tracked 24,205,409 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,330 research outputs from this source. They receive a mean Attention Score of 4.2. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 370,152 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.