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Mendeley readers
| Title |
Magnesium supplementation and high volume hydration reduce the renal toxicity caused by cisplatin-based chemotherapy in patients with lung cancer: a toxicity study
|
|---|---|
| Published in |
BMC Pharmacology and Toxicology, December 2014
|
| DOI | 10.1186/2050-6511-15-70 |
| Pubmed ID | |
| Authors |
Takako Oka, Tatsuo Kimura, Tomohiro Suzumura, Naoki Yoshimoto, Toshiyuki Nakai, Norio Yamamoto, Kuniomi Matsuura, Shigeki Mitsuoka, Naruo Yoshimura, Shinzoh Kudoh, Kazuto Hirata |
| Abstract |
Renal toxicity is a clinical problem that affects 28-42% of patients undergoing treatment with cisplatin. Renal toxicity can be minimized by high volume hydration with mannitol diuresis. Recent reports have shown that cisplatin induces depletion of Mg and that Mg supplementation can reduce renal toxicity. We hypothesized that Mg infusion combined with low volume hydration may not be sufficient to overcome cisplatin-induced renal toxicity. |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 3% |
| Unknown | 30 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 6 | 19% |
| Other | 4 | 13% |
| Researcher | 3 | 10% |
| Student > Master | 3 | 10% |
| Student > Postgraduate | 2 | 6% |
| Other | 5 | 16% |
| Unknown | 8 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 13 | 42% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 13% |
| Nursing and Health Professions | 3 | 10% |
| Agricultural and Biological Sciences | 1 | 3% |
| Unknown | 10 | 32% |