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Development of antimicrobial biomaterials produced from chitin-nanofiber sheet/silver nanoparticle composites

Overview of attention for article published in Journal of Nanobiotechnology, December 2014
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Title
Development of antimicrobial biomaterials produced from chitin-nanofiber sheet/silver nanoparticle composites
Published in
Journal of Nanobiotechnology, December 2014
DOI 10.1186/s12951-014-0049-1
Pubmed ID
Authors

Vinh Quang Nguyen, Masayuki Ishihara, Jun Kinoda, Hidemi Hattori, Shingo Nakamura, Takeshi Ono, Yasushi Miyahira, Takemi Matsui

Abstract

BackgroundChitin nanofibers sheets (CNFSs) with nanoscale fiber-like surface structures are nontoxic and biodegradable biomaterials with large surface-to-mass ratio. CNFSs are widely applied as biomedical materials such as a functional wound dressing. This study aimed to develop antimicrobial biomaterials made up of CNFS-immobilized silver nanoparticles (CNFS/Ag NPs).Materials and methodsCNFSs were immersed in suspensions of Ag NPs (5.17¿±¿1.9 nm in diameter; mean¿±¿SD) for 30 min at room temperature to produce CNFS/Ag NPs. CNFS/Ag NPs were characterized by transmission electron microscopy (TEM) and then tested for antimicrobial activities against Escherichia (E.) coli, Pseudomonas (P.) aeruginosa, and H1N1 influenza A virus, three pathogens that represent the most widespread infectious bacteria and viruses. Ultrathin sectioning of bacterial cells also was carried out to observe the bactericidal mechanism of Ag NPs.ResultsThe TEM images indicated that the Ag NPs are dispersed and tightly adsorbed onto CNFSs. Although CNFSs alone have only weak antimicrobial activity, CNFS/Ag NPs showed much stronger antimicrobial properties against E. coli, P. aeruginosa, and influenza A virus, with the amount of immobilized Ag NPs onto CNFSs.ConclusionsOur results suggest that CNFS/Ag NPs interacting with those microbes exhibit stronger antimicrobial activities, and that it is possible to apply CNFS/Ag NPs as anti-virus sheets as well as anti-infectious wound dressings.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Slovenia 1 1%
Unknown 81 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 24%
Student > Master 11 13%
Researcher 6 7%
Student > Doctoral Student 5 6%
Professor > Associate Professor 4 5%
Other 13 16%
Unknown 23 28%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 16%
Materials Science 10 12%
Chemistry 9 11%
Engineering 5 6%
Chemical Engineering 5 6%
Other 11 13%
Unknown 29 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 December 2014.
All research outputs
#15,311,799
of 22,772,779 outputs
Outputs from Journal of Nanobiotechnology
#647
of 1,404 outputs
Outputs of similar age
#213,671
of 360,895 outputs
Outputs of similar age from Journal of Nanobiotechnology
#6
of 15 outputs
Altmetric has tracked 22,772,779 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,404 research outputs from this source. They receive a mean Attention Score of 3.6. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 360,895 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.