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High hopes for cannabinoid agonists in the treatment of rheumatic diseases

Overview of attention for article published in BMC Musculoskeletal Disorders, December 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (74th percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

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7 X users
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66 Mendeley
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Title
High hopes for cannabinoid agonists in the treatment of rheumatic diseases
Published in
BMC Musculoskeletal Disorders, December 2014
DOI 10.1186/1471-2474-15-410
Pubmed ID
Authors

Caroline A Staunton, Ali Mobasheri, Richard Barrett-Jolley

Abstract

There are two well-characterised isoforms of cannabinoid receptor; CB1 and CB2 and of these CB2 is under active investigation as a potential target for treatment of the chronic pain associated with widespread and intractable joint diseases osteoarthritis and rheumatoid arthritis. The recent report by Fukuda et al (BMC Musculoskelet Disord15:275, 2014) in BMC Musculoskeletal Disorders investigates the efficacy of a selective CB2 agonist, JW133, in both in vitro and in vivo models of rheumatoid arthritis and provides encouraging data. The report shows that JW133 inhibits expression of the CCL2 cytokine, osteoclastogenesis and reduces histological indicators of joint degeneration. Each of these could potentially contribute to beneficial analgesic effects in a therapeutic context.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 3%
United States 1 2%
Unknown 63 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 15%
Student > Bachelor 8 12%
Student > Postgraduate 7 11%
Other 5 8%
Student > Master 5 8%
Other 14 21%
Unknown 17 26%
Readers by discipline Count As %
Medicine and Dentistry 20 30%
Agricultural and Biological Sciences 10 15%
Biochemistry, Genetics and Molecular Biology 4 6%
Veterinary Science and Veterinary Medicine 2 3%
Unspecified 2 3%
Other 10 15%
Unknown 18 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 May 2015.
All research outputs
#6,409,658
of 22,772,779 outputs
Outputs from BMC Musculoskeletal Disorders
#1,245
of 4,039 outputs
Outputs of similar age
#89,409
of 360,775 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#21
of 79 outputs
Altmetric has tracked 22,772,779 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 4,039 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 360,775 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 79 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.