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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Circulating miRNAs in cancer: from detection to therapy
|
|---|---|
| Published in |
Journal of Hematology & Oncology, December 2014
|
| DOI | 10.1186/s13045-014-0086-0 |
| Pubmed ID | |
| Authors |
Wen-Tao Wang, Yue-Qin Chen |
| Abstract |
Since the discovery of circulating microRNAs (miRNAs) in body fluids, an increasing number of studies have focused on their potential as non-invasive biomarkers and as therapeutic targets or tools for many diseases, particularly for cancers. Because of their stability, miRNAs are easily detectable in body fluids. Extracellular miRNAs have potential as biomarkers for the prediction and prognosis of cancer. Moreover, they also enable communication between cells within the tumor microenvironment, thereby influencing tumorigenesis. In this review, we summarize the progresses made over the past decade regarding circulating miRNAs, from the development of detection methods to their clinical application as biomarkers and therapeutic tools for cancer. We also discuss the advantages and limitations of different detection methods and the pathways of circulating miRNAs in cell-cell communication, in addition to their clinical pharmacokinetics and toxicity in human organs. Finally, we highlight the potential of circulating miRNAs in clinical applications for cancer. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Romania | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 108 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 18% |
| Student > Bachelor | 17 | 15% |
| Student > Master | 14 | 13% |
| Researcher | 13 | 12% |
| Student > Doctoral Student | 9 | 8% |
| Other | 23 | 21% |
| Unknown | 15 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 32 | 29% |
| Agricultural and Biological Sciences | 20 | 18% |
| Medicine and Dentistry | 15 | 14% |
| Chemistry | 6 | 5% |
| Engineering | 3 | 3% |
| Other | 14 | 13% |
| Unknown | 21 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2014.
All research outputs
#14,791,252
of 22,772,779 outputs
Outputs from Journal of Hematology & Oncology
#722
of 1,189 outputs
Outputs of similar age
#202,310
of 359,774 outputs
Outputs of similar age from Journal of Hematology & Oncology
#4
of 16 outputs
Altmetric has tracked 22,772,779 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,189 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.7. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 359,774 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.