Title |
Seasonal malaria chemoprevention: successes and missed opportunities
|
---|---|
Published in |
Malaria Journal, November 2017
|
DOI | 10.1186/s12936-017-2132-1 |
Pubmed ID | |
Authors |
Matthew E. Coldiron, Lorenz Von Seidlein, Rebecca F. Grais |
Abstract |
Seasonal malaria chemoprevention (SMC) was recommended in 2012 for young children in the Sahel during the peak malaria transmission season. Children are given a single dose of sulfadoxine/pyrimethamine combined with a 3-day course of amodiaquine, once a month for up to 4 months. Roll-out and scale-up of SMC has been impressive, with 12 million children receiving the intervention in 2016. There is evidence of its overall benefit in routine implementation settings, and a meta-analysis of clinical trial data showed a 75% decrease in clinical malaria compared to placebo. SMC is not free of shortcomings. Its target zone includes many hard-to-reach areas, both because of poor infrastructure and because of political instability. Treatment adherence to a 3-day course of preventive treatment has not been fully documented, and could prove challenging. As SMC is scaled up, integration into a broader, community-based paradigm which includes other preventive and curative activities may prove beneficial, both for health systems and for recipients. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 180 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 30 | 17% |
Researcher | 21 | 12% |
Student > Bachelor | 16 | 9% |
Student > Postgraduate | 10 | 6% |
Student > Ph. D. Student | 10 | 6% |
Other | 26 | 14% |
Unknown | 67 | 37% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 31 | 17% |
Nursing and Health Professions | 19 | 11% |
Agricultural and Biological Sciences | 16 | 9% |
Biochemistry, Genetics and Molecular Biology | 12 | 7% |
Immunology and Microbiology | 11 | 6% |
Other | 22 | 12% |
Unknown | 69 | 38% |