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Antiplasmodial activity of chloroquine analogs against chloroquine-resistant parasites, docking studies and mechanisms of drug action

Overview of attention for article published in Malaria Journal, December 2014
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1 X user

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60 Mendeley
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Title
Antiplasmodial activity of chloroquine analogs against chloroquine-resistant parasites, docking studies and mechanisms of drug action
Published in
Malaria Journal, December 2014
DOI 10.1186/1475-2875-13-469
Pubmed ID
Authors

Nicolli B de Souza, Arturene ML Carmo, Adilson D da Silva, Tanos CC França, Antoniana U Krettli

Abstract

Given the threat of resistance of human malaria parasites, including to artemisinin derivatives, new agents are needed. Chloroquine (CQ) has been the most widely used anti-malarial, and new analogs (CQAns) presenting alkynes and side chain variations with high antiplasmodial activity were evaluated.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Burkina Faso 1 2%
United States 1 2%
Unknown 57 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 22%
Student > Bachelor 7 12%
Lecturer 6 10%
Researcher 6 10%
Student > Master 6 10%
Other 10 17%
Unknown 12 20%
Readers by discipline Count As %
Chemistry 11 18%
Medicine and Dentistry 11 18%
Agricultural and Biological Sciences 8 13%
Pharmacology, Toxicology and Pharmaceutical Science 7 12%
Biochemistry, Genetics and Molecular Biology 5 8%
Other 4 7%
Unknown 14 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 December 2014.
All research outputs
#15,311,799
of 22,772,779 outputs
Outputs from Malaria Journal
#4,466
of 5,555 outputs
Outputs of similar age
#213,897
of 361,266 outputs
Outputs of similar age from Malaria Journal
#63
of 95 outputs
Altmetric has tracked 22,772,779 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,555 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,266 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 95 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.