Title |
Cigarette smoke induces epithelial to mesenchymal transition and increases the metastatic ability of breast cancer cells
|
---|---|
Published in |
Molecular Cancer, August 2013
|
DOI | 10.1186/1476-4598-12-90 |
Pubmed ID | |
Authors |
Francescopaolo Di Cello, V Lynn Flowers, Huili Li, Briana Vecchio-Pagán, Brent Gordon, Kirsten Harbom, James Shin, Robert Beaty, Wei Wang, Cory Brayton, Stephen B Baylin, Cynthia A Zahnow |
Abstract |
Recent epidemiological studies demonstrate that both active and involuntary exposure to tobacco smoke increase the risk of breast cancer. Little is known, however, about the molecular mechanisms by which continuous, long term exposure to tobacco smoke contributes to breast carcinogenesis because most previous studies have focused on short term treatment models. In this work we have set out to investigate the progressive transforming effects of tobacco smoke on non-tumorigenic mammary epithelial cells and breast cancer cells using in vitro and in vivo models of chronic cigarette smoke exposure. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Norway | 1 | 2% |
Unknown | 62 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 12 | 19% |
Student > Ph. D. Student | 11 | 17% |
Student > Master | 8 | 13% |
Student > Doctoral Student | 5 | 8% |
Researcher | 4 | 6% |
Other | 6 | 10% |
Unknown | 17 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 15 | 24% |
Biochemistry, Genetics and Molecular Biology | 12 | 19% |
Agricultural and Biological Sciences | 7 | 11% |
Nursing and Health Professions | 5 | 8% |
Chemistry | 2 | 3% |
Other | 4 | 6% |
Unknown | 18 | 29% |