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Cigarette smoke induces epithelial to mesenchymal transition and increases the metastatic ability of breast cancer cells

Overview of attention for article published in Molecular Cancer, August 2013
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Title
Cigarette smoke induces epithelial to mesenchymal transition and increases the metastatic ability of breast cancer cells
Published in
Molecular Cancer, August 2013
DOI 10.1186/1476-4598-12-90
Pubmed ID
Authors

Francescopaolo Di Cello, V Lynn Flowers, Huili Li, Briana Vecchio-Pagán, Brent Gordon, Kirsten Harbom, James Shin, Robert Beaty, Wei Wang, Cory Brayton, Stephen B Baylin, Cynthia A Zahnow

Abstract

Recent epidemiological studies demonstrate that both active and involuntary exposure to tobacco smoke increase the risk of breast cancer. Little is known, however, about the molecular mechanisms by which continuous, long term exposure to tobacco smoke contributes to breast carcinogenesis because most previous studies have focused on short term treatment models. In this work we have set out to investigate the progressive transforming effects of tobacco smoke on non-tumorigenic mammary epithelial cells and breast cancer cells using in vitro and in vivo models of chronic cigarette smoke exposure.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Norway 1 2%
Unknown 62 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 12 19%
Student > Ph. D. Student 11 17%
Student > Master 8 13%
Student > Doctoral Student 5 8%
Researcher 4 6%
Other 6 10%
Unknown 17 27%
Readers by discipline Count As %
Medicine and Dentistry 15 24%
Biochemistry, Genetics and Molecular Biology 12 19%
Agricultural and Biological Sciences 7 11%
Nursing and Health Professions 5 8%
Chemistry 2 3%
Other 4 6%
Unknown 18 29%