Title |
Role of adiponectin and proinflammatory gene expression in adipose tissue chronic inflammation in women with metabolic syndrome
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Published in |
Diabetology & Metabolic Syndrome, December 2014
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DOI | 10.1186/1758-5996-6-137 |
Pubmed ID | |
Authors |
Larisa Litvinova, Dmitriy Atochin, Mariia Vasilenko, Nikolai Fattakhov, Pavel Zatolokin, Igor Vaysbeyn, Elena Kirienkova |
Abstract |
The purpose of this research was to study the gene expression of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), nuclear factor kappa B (NF-κB), vascular endothelial growth factor A (VEGF-A) and adiponectin (AdipoQ) genes in the visceral (omental, mesenteric) and subcutaneous adipose tissue depots in metabolic syndrome (MS). We studied 23 women with MS, with a mean age of 50.7 ± 4.5 years and mean body mass index (BMI) of 45.6 ± 9.8 kg/m(2). The control group included 10 women, with a mean age of 40.6 ± 8.7 years and normal BMI (22.3 ± 3.7 kg/m(2)). The gene expression levels in the omental (OAT), mesenteric (MAT) and subcutaneous (SAT) adipose tissues were assessed by quantitative real-time PCR. |
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Unknown | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 26 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 8 | 31% |
Professor | 4 | 15% |
Researcher | 4 | 15% |
Student > Bachelor | 2 | 8% |
Student > Ph. D. Student | 1 | 4% |
Other | 2 | 8% |
Unknown | 5 | 19% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 7 | 27% |
Agricultural and Biological Sciences | 4 | 15% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 8% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Nursing and Health Professions | 1 | 4% |
Other | 2 | 8% |
Unknown | 9 | 35% |