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Phosphorylated tau/amyloid beta 1-42 ratio in ventricular cerebrospinal fluid reflects outcome in idiopathic normal pressure hydrocephalus

Overview of attention for article published in Fluids and Barriers of the CNS, March 2012
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Title
Phosphorylated tau/amyloid beta 1-42 ratio in ventricular cerebrospinal fluid reflects outcome in idiopathic normal pressure hydrocephalus
Published in
Fluids and Barriers of the CNS, March 2012
DOI 10.1186/2045-8118-9-7
Pubmed ID
Authors

Sunil Patel, Edward B Lee, Sharon X Xie, Anica Law, Eric M Jackson, Steven E Arnold, Christopher M Clark, Leslie M Shaw, M Sean Grady, John Q Trojanowski, Roy H Hamilton

Abstract

Idiopathic normal pressure hydrocephalus (iNPH) is a potentially reversible cause of dementia and gait disturbance that is typically treated by operative placement of a ventriculoperitoneal shunt. The outcome from shunting is variable, and some evidence suggests that the presence of comorbid Alzheimer's disease (AD) may impact shunt outcome. Evidence also suggests that AD biomarkers in cerebrospinal fluid (CSF) may predict the presence of AD. The aim of this study was to investigate the relationship between the phosphorylated tau/amyloid beta 1-42 (ptau/Aβ1-42) ratio in ventricular CSF and shunt outcome in patients with iNPH.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 2 3%
Netherlands 1 2%
Germany 1 2%
United Kingdom 1 2%
Australia 1 2%
Unknown 59 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 17%
Student > Ph. D. Student 8 12%
Student > Postgraduate 7 11%
Other 6 9%
Student > Bachelor 5 8%
Other 15 23%
Unknown 13 20%
Readers by discipline Count As %
Medicine and Dentistry 25 38%
Neuroscience 9 14%
Agricultural and Biological Sciences 4 6%
Psychology 3 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 4 6%
Unknown 18 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2014.
All research outputs
#20,246,428
of 22,774,233 outputs
Outputs from Fluids and Barriers of the CNS
#318
of 361 outputs
Outputs of similar age
#145,493
of 160,656 outputs
Outputs of similar age from Fluids and Barriers of the CNS
#1
of 2 outputs
Altmetric has tracked 22,774,233 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 361 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 160,656 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them