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The case for decoupling assembly and submission standards to maintain a more flexible registry of biological parts

Overview of attention for article published in Journal of Biological Engineering, December 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#28 of 286)
  • High Attention Score compared to outputs of the same age (92nd percentile)

Mentioned by

blogs
1 blog
twitter
13 X users
facebook
1 Facebook page
reddit
1 Redditor

Citations

dimensions_citation
7 Dimensions

Readers on

mendeley
28 Mendeley
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Title
The case for decoupling assembly and submission standards to maintain a more flexible registry of biological parts
Published in
Journal of Biological Engineering, December 2014
DOI 10.1186/1754-1611-8-28
Pubmed ID
Authors

Razan N Alnahhas, Ben Slater, Yunle Huang, Catherine Mortensen, Jordan W Monk, Yousef Okasheh, Marco D Howard, Neil R Gottel, Michael J Hammerling, Jeffrey E Barrick

Abstract

The Registry of Standard Biological Parts only accepts genetic parts compatible with the RFC 10 BioBrick format. This combined assembly and submission standard requires that four unique restriction enzyme sites must not occur in the DNA sequence encoding a part. We present evidence that this requirement places a nontrivial burden on iGEM teams developing large and novel parts. We further argue that the emergence of inexpensive DNA synthesis and versatile assembly methods reduces the utility of coupling submission and assembly standards and propose a submission standard that is compatible with current quality control strategies while nearly eliminating sequence constraints on submitted parts.

X Demographics

X Demographics

The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 14%
United Kingdom 1 4%
Spain 1 4%
China 1 4%
Unknown 21 75%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 36%
Student > Ph. D. Student 8 29%
Student > Bachelor 6 21%
Professor 2 7%
Other 1 4%
Other 1 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 64%
Biochemistry, Genetics and Molecular Biology 4 14%
Social Sciences 2 7%
Nursing and Health Professions 1 4%
Immunology and Microbiology 1 4%
Other 1 4%
Unknown 1 4%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 June 2015.
All research outputs
#2,041,569
of 24,063,285 outputs
Outputs from Journal of Biological Engineering
#28
of 286 outputs
Outputs of similar age
#28,844
of 369,693 outputs
Outputs of similar age from Journal of Biological Engineering
#2
of 4 outputs
Altmetric has tracked 24,063,285 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 286 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.5. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 369,693 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.