Title |
Incomplete evidence: the inadequacy of databases in tracing published adverse drug reactions in clinical trials
|
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Published in |
BMC Medical Research Methodology, September 2001
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DOI | 10.1186/1471-2288-1-7 |
Pubmed ID | |
Authors |
Sheena Derry, Yoon Kong Loke, Jeffrey K Aronson |
Abstract |
We would expect information on adverse drug reactions in randomised clinical trials to be easily retrievable from specific searches of electronic databases. However, complete retrieval of such information may not be straightforward, for two reasons. First, not all clinical drug trials provide data on the frequency of adverse effects. Secondly, not all electronic records of trials include terms in the abstract or indexing fields that enable us to select those with adverse effects data. We have determined how often automated search methods, using indexing terms and/or textwords in the title or abstract, would fail to retrieve trials with adverse effects data. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 4% |
Germany | 1 | 2% |
Canada | 1 | 2% |
Unknown | 45 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 13 | 27% |
Librarian | 7 | 14% |
Student > Ph. D. Student | 7 | 14% |
Student > Master | 4 | 8% |
Student > Postgraduate | 3 | 6% |
Other | 8 | 16% |
Unknown | 7 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 23 | 47% |
Economics, Econometrics and Finance | 4 | 8% |
Social Sciences | 3 | 6% |
Mathematics | 1 | 2% |
Agricultural and Biological Sciences | 1 | 2% |
Other | 5 | 10% |
Unknown | 12 | 24% |