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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Establishment of the neurogenic boundary of the mouse retina requires cooperation of SOX2 and WNT signaling
|
|---|---|
| Published in |
Neural Development, December 2014
|
| DOI | 10.1186/1749-8104-9-27 |
| Pubmed ID | |
| Authors |
Whitney E Heavner, Cynthia L Andoniadou, Larysa H Pevny |
| Abstract |
Eye development in vertebrates relies on the critical regulation of SOX2 expression. Humans with mutations in SOX2 often suffer from eye defects including anophthalmia (no eye) and microphthalmia (small eye). In mice, deletion of Sox2 in optic cup progenitor cells results in loss of neural competence and cell fate conversion of the neural retina to a non-neurogenic fate, specifically the acquisition of fate associated with progenitors of the ciliary epithelium. This fate is also promoted with constitutive expression of stabilized beta-Catenin in the optic cup, where the WNT pathway is up-regulated. We addressed whether SOX2 co-ordinates the neurogenic boundary of the retina through modulating the WNT/beta-Catenin pathway by using a genetic approach in the mouse. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| United Kingdom | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Finland | 1 | 2% |
| Unknown | 47 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 25% |
| Student > Master | 8 | 17% |
| Researcher | 6 | 13% |
| Student > Bachelor | 5 | 10% |
| Professor > Associate Professor | 5 | 10% |
| Other | 7 | 15% |
| Unknown | 5 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 18 | 38% |
| Biochemistry, Genetics and Molecular Biology | 13 | 27% |
| Medicine and Dentistry | 3 | 6% |
| Neuroscience | 3 | 6% |
| Immunology and Microbiology | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 9 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2014.
All research outputs
#12,615,710
of 22,774,233 outputs
Outputs from Neural Development
#82
of 226 outputs
Outputs of similar age
#164,853
of 361,040 outputs
Outputs of similar age from Neural Development
#1
of 6 outputs
Altmetric has tracked 22,774,233 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 226 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,040 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them