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X Demographics
Mendeley readers
Attention Score in Context
| Title |
CCL2 modulates cytokine production in cultured mouse astrocytes
|
|---|---|
| Published in |
Journal of Neuroinflammation, October 2010
|
| DOI | 10.1186/1742-2094-7-67 |
| Pubmed ID | |
| Authors |
Bridgette D Semple, Tony Frugier, M Cristina Morganti-Kossmann |
| Abstract |
The chemokine CCL2 (also known as monocyte chemoattractant protein-1, or MCP-1) is upregulated in patients and rodent models of traumatic brain injury (TBI), contributing to post-traumatic neuroinflammation and degeneration by directing the infiltration of blood-derived macrophages into the injured brain. Our laboratory has previously reported that Ccl2-/- mice show reduced macrophage accumulation and tissue damage, corresponding to improved motor recovery, following experimental TBI. Surprisingly, Ccl2-deficient mice also exhibited delayed but exacerbated secretion of key proinflammatory cytokines in the injured cortex. Thus we sought to further characterise CCL2's potential ability to modulate immunoactivation of astrocytes in vitro. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Australia | 1 | 2% |
| Unknown | 64 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 29% |
| Researcher | 7 | 11% |
| Student > Doctoral Student | 7 | 11% |
| Student > Bachelor | 6 | 9% |
| Student > Master | 6 | 9% |
| Other | 10 | 15% |
| Unknown | 11 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 17 | 26% |
| Medicine and Dentistry | 9 | 14% |
| Biochemistry, Genetics and Molecular Biology | 8 | 12% |
| Neuroscience | 8 | 12% |
| Immunology and Microbiology | 4 | 6% |
| Other | 8 | 12% |
| Unknown | 12 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2014.
All research outputs
#13,418,483
of 22,774,233 outputs
Outputs from Journal of Neuroinflammation
#1,441
of 2,622 outputs
Outputs of similar age
#76,169
of 98,969 outputs
Outputs of similar age from Journal of Neuroinflammation
#8
of 12 outputs
Altmetric has tracked 22,774,233 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,622 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 98,969 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.