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Mendeley readers
| Title |
Screening and treatment of psychological distress in patients with metastatic colorectal cancer: study protocol of the TES trial
|
|---|---|
| Published in |
BMC Cancer, April 2015
|
| DOI | 10.1186/s12885-015-1313-y |
| Pubmed ID | |
| Authors |
Claudia SEW Schuurhuizen, Annemarie MJ Braamse, Aartjan TF Beekman, Hanna Bomhof-Roordink, Judith E Bosmans, Pim Cuijpers, Adriaan W Hoogendoorn, Inge RHM Konings, Mecheline HM van der Linden, Elisabeth CW Neefjes, Henk MW Verheul, Joost Dekker |
| Abstract |
Psychological distress occurs frequently in patients with cancer. Psychological distress includes mild and severe forms of both anxious and depressive mood states. Literature indicates that effective management of psychological distress seems to require targeted selection of patients (T), followed by enhanced care (E), and the application of evidence based interventions. Besides, it is hypothesized that delivering care according to the stepped care (S) approach results in an affordable program. The aim of the current study is to evaluate the (cost)-effectiveness of the TES program compared to usual care in reducing psychological distress in patients with metastatic colorectal cancer (mCRC). This study is designed as a cluster randomized trial with 2 treatment arms: TES program for screening and treatment of psychological distress versus usual care. Sixteen hospitals participate in this study, recruiting patients with mCRC. Outcomes are evaluated at the beginning of chemotherapy and after 3, 10, 24, and 48 weeks. Primary outcome is the difference in treatment effect over time in psychological distress, assessed with the Hospital Anxiety and Depression Scale. Secondary outcomes include quality of life, patient evaluation of care, recognition and management of psychological distress, and societal costs. We created optimal conditions for an effective screening and treatment program for psychological distress in patients with mCRC. This involves targeted selection of patients, followed by enhanced and stepped care. Our approach will be thoroughly evaluated in this study. We expect that our results will contribute to the continuing debate on the (cost-) effectiveness of screening for and treatment of psychological distress in patients with cancer. This trial is registered in the Netherlands Trial Register NTR4034. |
Mendeley readers
The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 108 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 20 | 18% |
| Researcher | 13 | 12% |
| Student > Ph. D. Student | 12 | 11% |
| Student > Bachelor | 8 | 7% |
| Student > Postgraduate | 6 | 6% |
| Other | 21 | 19% |
| Unknown | 29 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 26 | 24% |
| Medicine and Dentistry | 24 | 22% |
| Nursing and Health Professions | 10 | 9% |
| Social Sciences | 2 | 2% |
| Biochemistry, Genetics and Molecular Biology | 1 | <1% |
| Other | 7 | 6% |
| Unknown | 39 | 36% |