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Prediction of methotrexate efficacy and adverse events in patients with juvenile idiopathic arthritis: a systematic literature review

Overview of attention for article published in Pediatric Rheumatology, December 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

news
1 news outlet
twitter
5 X users

Citations

dimensions_citation
28 Dimensions

Readers on

mendeley
75 Mendeley
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Title
Prediction of methotrexate efficacy and adverse events in patients with juvenile idiopathic arthritis: a systematic literature review
Published in
Pediatric Rheumatology, December 2014
DOI 10.1186/1546-0096-12-51
Pubmed ID
Authors

EH Pieter van Dijkhuizen, Nico M Wulffraat

Abstract

Methotrexate (MTX) is the cornerstone disease-modifying anti-rheumatic drug in juvenile idiopathic arthritis (JIA). In JIA, it is important to start effective treatment early to avoid long-term sequelae, such as joint damage. To accomplish this goal, it is crucial to know beforehand who is going to respond well to MTX. In addition, MTX adverse effects such as MTX intolerance occur frequently, potentially hindering its efficacy. To avoid inefficacy of an otherwise effective drug, the physician should be timely aware of these adverse events. Consequently, to optimise treatment of JIA patients with MTX, predictors for efficacy and adverse events should be used in daily clinical practice. The aim of this study was to summarise the existing knowledge about such predictors.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Singapore 1 1%
South Africa 1 1%
Canada 1 1%
Unknown 72 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 19%
Researcher 9 12%
Student > Bachelor 9 12%
Other 8 11%
Student > Master 8 11%
Other 15 20%
Unknown 12 16%
Readers by discipline Count As %
Medicine and Dentistry 40 53%
Agricultural and Biological Sciences 7 9%
Pharmacology, Toxicology and Pharmaceutical Science 5 7%
Biochemistry, Genetics and Molecular Biology 3 4%
Psychology 3 4%
Other 4 5%
Unknown 13 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 February 2015.
All research outputs
#2,437,734
of 22,774,233 outputs
Outputs from Pediatric Rheumatology
#85
of 693 outputs
Outputs of similar age
#36,670
of 361,188 outputs
Outputs of similar age from Pediatric Rheumatology
#2
of 8 outputs
Altmetric has tracked 22,774,233 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 693 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,188 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.