Title |
Implication of plasma intermedin levels in patients who underwent first-time diagnostic coronary angiography: a single centre, cross-sectional study
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Published in |
BMC Cardiovascular Disorders, December 2014
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DOI | 10.1186/1471-2261-14-182 |
Pubmed ID | |
Authors |
Aylin Hatice Yamac, Ahmet Bacaksiz, Ziya Ismailoglu, Sitki Kucukbuzcu, Emrah Sevgili, Emin Asoglu, Muharrem Nasifov, Parviz Jafarov, Ercan Erdogan, Omer Goktekin |
Abstract |
Intermedin (IMD) is involved in the prevention of atherosclerotic plaque progression, possessing cardioprotective effects from hypertrophy, fibrosis and ischemia-reperfusion injury. Elevated plasma IMD levels have been demonstrated in patients with acute coronary syndromes. No human study has examined the role of IMD in stable patients who underwent diagnostic coronary angiography with suspicion of coronary artery disease (CAD). Thus we investigated the role of IMD as a biomarker to discriminate patients with CAD and predict those with severe disease who require early and intensive therapeutic intervention before presenting with acute coronary syndrome. |
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