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The involvement of miR-100 in bladder urothelial carcinogenesis changing the expression levels of mRNA and proteins of genes related to cell proliferation, survival, apoptosis and chromosomal…

Overview of attention for article published in Cancer Cell International, November 2014
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Title
The involvement of miR-100 in bladder urothelial carcinogenesis changing the expression levels of mRNA and proteins of genes related to cell proliferation, survival, apoptosis and chromosomal stability
Published in
Cancer Cell International, November 2014
DOI 10.1186/s12935-014-0119-3
Pubmed ID
Authors

Denis R Morais, Sabrina T Reis, Nayara Viana, Camila Berfort Piantino, Cristina Massoco, Caio Moura, Nelson Dip, Iran A Silva, Miguel Srougi, Katia RM Leite

Abstract

MicroRNAs (miRNA) are small non-coding RNAs that play an important role in the control of gene expression by inhibiting protein translation or promoting messenger RNA degradation. Today, miRNAs have been shown to be involved in various physiological and pathological cellular processes, including cancer, where they can act as oncogenes or tumor suppressor genes. Recently, lowered expression of miR-100, resulting in upregulation of FGFR3, has been correlated with low-grade, non-invasive bladder urothelial cancer, as an alternative oncogenesis pathway to the typical FGFR3 gene mutation. Our aim is to analyze the role of miR-100 in bladder cancer cell lines in controlling the expression of some of its possible target genes, including FGFR3 and its relationship with proliferation, apoptosis and DNA ploidy.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 6%
Unknown 16 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 35%
Researcher 5 29%
Professor 1 6%
Student > Doctoral Student 1 6%
Professor > Associate Professor 1 6%
Other 0 0%
Unknown 3 18%
Readers by discipline Count As %
Medicine and Dentistry 7 41%
Agricultural and Biological Sciences 3 18%
Biochemistry, Genetics and Molecular Biology 1 6%
Veterinary Science and Veterinary Medicine 1 6%
Environmental Science 1 6%
Other 1 6%
Unknown 3 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2014.
All research outputs
#20,246,428
of 22,774,233 outputs
Outputs from Cancer Cell International
#1,350
of 1,794 outputs
Outputs of similar age
#303,108
of 361,963 outputs
Outputs of similar age from Cancer Cell International
#17
of 22 outputs
Altmetric has tracked 22,774,233 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,794 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,963 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.