Title |
Chaperone-usher fimbriae in a diverse selection of Gallibacterium genomes
|
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Published in |
BMC Genomics, December 2014
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DOI | 10.1186/1471-2164-15-1093 |
Pubmed ID | |
Authors |
Eglė Kudirkienė, Ragnhild J Bager, Timothy J Johnson, Anders M Bojesen |
Abstract |
Fimbriae are bacterial cell surface organelles involved in the pathogenesis of many bacterial species, including Gallibacterium anatis, in which a F17-like fimbriae of the chaperone-usher (CU) family was recently shown to be an important virulence factor and vaccine candidate. To reveal the distribution and variability of CU fimbriae 22 genomes of the avian host-restricted bacteria Gallibacterium spp. were investigated. Fimbrial clusters were classified using phylogeny-based and conserved domain (CD) distribution-based approaches. To characterize the fimbriae in depth evolutionary analysis and in vitro expression of the most prevalent fimbrial clusters was performed. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 25% |
Other | 3 | 13% |
Student > Bachelor | 2 | 8% |
Student > Master | 2 | 8% |
Student > Ph. D. Student | 1 | 4% |
Other | 2 | 8% |
Unknown | 8 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 5 | 21% |
Agricultural and Biological Sciences | 4 | 17% |
Biochemistry, Genetics and Molecular Biology | 3 | 13% |
Computer Science | 2 | 8% |
Nursing and Health Professions | 1 | 4% |
Other | 1 | 4% |
Unknown | 8 | 33% |