Title |
Mesenchymal properties of SJL mice-stem cells and their efficacy as autologous therapy in a relapsing–remitting multiple sclerosis model
|
---|---|
Published in |
Stem Cell Research & Therapy, December 2014
|
DOI | 10.1186/scrt524 |
Pubmed ID | |
Authors |
Carmen Marin-Bañasco, Margarita Suardíaz García, Issac Hurtado Guerrero, Rafael Maldonado Sánchez, Guillermo Estivill-Torrús, Laura Leyva Fernández, Oscar Fernández Fernández |
Abstract |
Mesenchymal stem cells (MSCs) are a multipotent population of adult stem cells, which may represent a promising therapeutic approach for neurological autoimmune diseases such as multiple sclerosis. The mouse is the most used species for obtaining and studying the characteristics of MSC and their potential as autologous transplants in pre-clinical models. However, conflicting data have been published disclosing intraspecies variations. The choice of the mouse strain and the tissue source appear, among others, as important factors in the experimental application of MSCs. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 3% |
Unknown | 32 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 21% |
Student > Bachelor | 6 | 18% |
Student > Master | 4 | 12% |
Other | 3 | 9% |
Student > Ph. D. Student | 2 | 6% |
Other | 2 | 6% |
Unknown | 9 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 24% |
Agricultural and Biological Sciences | 7 | 21% |
Biochemistry, Genetics and Molecular Biology | 3 | 9% |
Neuroscience | 2 | 6% |
Energy | 1 | 3% |
Other | 3 | 9% |
Unknown | 9 | 27% |