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Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening

Overview of attention for article published in BMC Cancer, December 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

news
1 news outlet
twitter
1 X user

Readers on

mendeley
45 Mendeley
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Title
Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening
Published in
BMC Cancer, December 2014
DOI 10.1186/1471-2407-14-944
Pubmed ID
Authors

Zongxiang Zhou, Manishha Patel, Nicholas Ng, Mindy H Hsieh, Anthony P Orth, John R Walker, Serge Batalov, Jennifer L Harris, Jun Liu

Abstract

MYC family members are among the most frequently deregulated oncogenes in human cancers, yet direct therapeutic targeting of MYC in cancer has been challenging thus far. Synthetic lethality provides an opportunity for therapeutic intervention of MYC-driven cancers.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
Unknown 44 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 29%
Student > Ph. D. Student 12 27%
Student > Bachelor 5 11%
Student > Master 5 11%
Student > Postgraduate 2 4%
Other 2 4%
Unknown 6 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 27%
Biochemistry, Genetics and Molecular Biology 12 27%
Medicine and Dentistry 6 13%
Psychology 2 4%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 3 7%
Unknown 9 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 December 2014.
All research outputs
#3,114,800
of 22,774,233 outputs
Outputs from BMC Cancer
#700
of 8,283 outputs
Outputs of similar age
#46,070
of 354,732 outputs
Outputs of similar age from BMC Cancer
#12
of 158 outputs
Altmetric has tracked 22,774,233 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,283 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 354,732 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 158 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.