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Characterizing heterogeneity in leukemic cells using single-cell gene expression analysis

Overview of attention for article published in Genome Biology, December 2014
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Title
Characterizing heterogeneity in leukemic cells using single-cell gene expression analysis
Published in
Genome Biology, December 2014
DOI 10.1186/s13059-014-0525-9
Pubmed ID
Authors

Assieh Saadatpour, Guoji Guo, Stuart H Orkin, Guo-Cheng Yuan

Abstract

A fundamental challenge for cancer therapy is that each tumor contains a highly heterogeneous cell population whose structure and mechanistic underpinnings remain incompletely understood. Recent advances in single-cell gene expression profiling have created new possibilities to characterize this heterogeneity and to dissect the potential intra-cancer cellular hierarchy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 158 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 1%
United States 2 1%
Sweden 1 <1%
France 1 <1%
Unknown 152 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 54 34%
Researcher 34 22%
Student > Bachelor 15 9%
Student > Master 13 8%
Student > Postgraduate 10 6%
Other 14 9%
Unknown 18 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 55 35%
Biochemistry, Genetics and Molecular Biology 48 30%
Medicine and Dentistry 10 6%
Computer Science 8 5%
Immunology and Microbiology 4 3%
Other 11 7%
Unknown 22 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2014.
All research outputs
#14,915,476
of 25,374,917 outputs
Outputs from Genome Biology
#3,897
of 4,467 outputs
Outputs of similar age
#188,215
of 368,291 outputs
Outputs of similar age from Genome Biology
#91
of 101 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 368,291 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 101 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.