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Mendeley readers
| Title |
Effects of high-frequency transcranial magnetic stimulation on functional performance in individuals with incomplete spinal cord injury: study protocol for a randomized controlled trial
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|---|---|
| Published in |
Trials, November 2017
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| DOI | 10.1186/s13063-017-2280-1 |
| Pubmed ID | |
| Authors |
Amanda Vitória Lacerda de Araújo, Valéria Ribeiro Nogueira Barbosa, Gilma Serra Galdino, Felipe Fregni, Thais Massetti, Sara Lynn Fontes, Danilo de Oliveira Silva, Talita Dias da Silva, Carlos Bandeira de Mello Monteiro, James Tonks, Fernando Henrique Magalhães |
| Abstract |
Repetitive transcranial magnetic stimulation (rTMS) has been investigated as a new tool in neurological rehabilitation of individuals with spinal cord injury (SCI). However, due to the inconsistent results regarding the effects of rTMS in people with SCI, a randomized controlled double-blind crossover trial is needed to clarify the clinical utility and to assess the effect size of rTMS intervention in this population. Therefore, this paper describes a study protocol designed to investigate whether the use of rTMS can improve the motor and sensory function, as well as reduce spasticity in patients with incomplete SCI. A double-blind randomized sham-controlled crossover trial will be performed by enrolling 20 individuals with incomplete SCI. Patients who are at least six months post incomplete SCI (aged 18-60 years) will be recruited through referral by medical practitioners or therapists. Individuals will be randomly assigned to either group 1 or group 2 in a 1:1 ratio, with ten individuals in each group. The rTMS protocol will include ten sessions of high-frequency rTMS (5 Hz) over the bilateral lower-limb motor area positioned at the vertex (Cz). Clinical evaluations will be performed at baseline and after rTMS active and sham. rTMS has produced positive results in treating individuals with physical impairments; thus, it might be promising in the SCI population. The results of this study may provide new insights to motor rehabilitation thereby contributing towards the better usage of rTMS in the SCI population. ClinicalTrials.gov, NCT02899637 . Registered on 25 August 2016. |
Mendeley readers
The data shown below were compiled from readership statistics for 156 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 156 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 24 | 15% |
| Researcher | 17 | 11% |
| Student > Ph. D. Student | 13 | 8% |
| Student > Master | 12 | 8% |
| Student > Doctoral Student | 10 | 6% |
| Other | 23 | 15% |
| Unknown | 57 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 25 | 16% |
| Nursing and Health Professions | 22 | 14% |
| Neuroscience | 20 | 13% |
| Psychology | 5 | 3% |
| Engineering | 5 | 3% |
| Other | 19 | 12% |
| Unknown | 60 | 38% |