Title |
Multiple intracranial and spinal metastases from a nonfunctioning pituitary adenoma following multiple surgeries: an illustrative case with 16 years of follow-up
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Published in |
World Journal of Surgical Oncology, December 2014
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DOI | 10.1186/1477-7819-12-380 |
Pubmed ID | |
Authors |
Jun Wang, Er-meng Ma, Peng-fei Wu, Bo Qiu and, Yun-jie Wang |
Abstract |
Pituitary adenomas are the third most common primary intracranial tumor; however, those with postoperative metastases are very rare and are classically considered as pituitary carcinomas. The field of neurosurgery has struggled with diagnosing and treating these unusual lesions. In this report, we retrospectively analyze the clinical features, imaging findings, pathological characteristics and prognosis of one patient with non-hormone-secreting pituitary adenoma who had multiple intracranial and spinal metastases and underwent four surgeries in a 16-year follow-up period. In addition, on the basis of the existing literature, we explore the underlying mechanisms of, as well as the preventive and therapeutic strategies used to treat, pituitary carcinomas and postoperative metastasis of pituitary tumors. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 2 | 67% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Belgium | 1 | 6% |
Unknown | 17 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 6 | 33% |
Student > Postgraduate | 3 | 17% |
Researcher | 3 | 17% |
Student > Bachelor | 1 | 6% |
Other | 1 | 6% |
Other | 2 | 11% |
Unknown | 2 | 11% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 8 | 44% |
Agricultural and Biological Sciences | 2 | 11% |
Neuroscience | 2 | 11% |
Psychology | 1 | 6% |
Nursing and Health Professions | 1 | 6% |
Other | 0 | 0% |
Unknown | 4 | 22% |