Title |
Development of a colloidal gold-based lateral flow dipstick immunoassay for rapid qualitative and semi-quantitative analysis of artesunate and dihydroartemisinin
|
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Published in |
Malaria Journal, March 2014
|
DOI | 10.1186/1475-2875-13-127 |
Pubmed ID | |
Authors |
Lishan He, Tiegui Nan, Yongliang Cui, Suqin Guo, Wei Zhang, Rui Zhang, Guiyu Tan, Baomin Wang, Liwang Cui |
Abstract |
Artemisinin-based combination therapy (ACT) plays an indispensable role in malaria control and elimination. However, the circulation of counterfeit, substandard drugs has greatly threatened malaria elimination campaigns. Most methods for the analysis of artemisinin and its derivatives require expensive equipment and sophisticated instrumentation. A convenient, easy-to-use diagnostic device for rapid evaluation of the quality of artemisinin drugs at the point-of-care is still lacking. In this study a lateral flow dipstick immunoassay was developed for qualitative and semi-quantitative analysis of artesunate (ATS) and dihydroartemisinin (DHA) in anti-malarial drugs. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Malaysia | 1 | 1% |
United Kingdom | 1 | 1% |
United States | 1 | 1% |
Switzerland | 1 | 1% |
Unknown | 67 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 16 | 23% |
Student > Ph. D. Student | 12 | 17% |
Researcher | 11 | 15% |
Other | 9 | 13% |
Student > Doctoral Student | 5 | 7% |
Other | 13 | 18% |
Unknown | 5 | 7% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 13 | 18% |
Medicine and Dentistry | 12 | 17% |
Pharmacology, Toxicology and Pharmaceutical Science | 10 | 14% |
Chemistry | 9 | 13% |
Biochemistry, Genetics and Molecular Biology | 7 | 10% |
Other | 14 | 20% |
Unknown | 6 | 8% |