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Mitochondrial genomic variation associated with higher mitochondrial copy number: the Cache County Study on Memory Health and Aging

Overview of attention for article published in BMC Bioinformatics, May 2014
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Title
Mitochondrial genomic variation associated with higher mitochondrial copy number: the Cache County Study on Memory Health and Aging
Published in
BMC Bioinformatics, May 2014
DOI 10.1186/1471-2105-15-s7-s6
Pubmed ID
Authors

Perry G Ridge, Taylor J Maxwell, Spencer J Foutz, Matthew H Bailey, Christopher D Corcoran, JoAnn T Tschanz, Maria C Norton, Ronald G Munger, Elizabeth O'Brien, Richard A Kerber, Richard M Cawthon, John SK Kauwe

Abstract

The mitochondria are essential organelles and are the location of cellular respiration, which is responsible for the majority of ATP production. Each cell contains multiple mitochondria, and each mitochondrion contains multiple copies of its own circular genome. The ratio of mitochondrial genomes to nuclear genomes is referred to as mitochondrial copy number. Decreases in mitochondrial copy number are known to occur in many tissues as people age, and in certain diseases. The regulation of mitochondrial copy number by nuclear genes has been studied extensively. While mitochondrial variation has been associated with longevity and some of the diseases known to have reduced mitochondrial copy number, the role that the mitochondrial genome itself has in regulating mitochondrial copy number remains poorly understood.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 2%
United States 1 2%
Unknown 48 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 20%
Student > Ph. D. Student 9 18%
Student > Master 6 12%
Student > Doctoral Student 5 10%
Student > Bachelor 4 8%
Other 8 16%
Unknown 8 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 12 24%
Agricultural and Biological Sciences 11 22%
Medicine and Dentistry 6 12%
Neuroscience 3 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 5 10%
Unknown 11 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 December 2014.
All research outputs
#18,386,678
of 22,774,233 outputs
Outputs from BMC Bioinformatics
#6,306
of 7,276 outputs
Outputs of similar age
#163,146
of 226,706 outputs
Outputs of similar age from BMC Bioinformatics
#117
of 153 outputs
Altmetric has tracked 22,774,233 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,276 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,706 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 153 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.