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Sunitinib-induced severe toxicities in a Japanese patient with the ABCG2 421 AA genotype

Overview of attention for article published in BMC Cancer, December 2014
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Title
Sunitinib-induced severe toxicities in a Japanese patient with the ABCG2 421 AA genotype
Published in
BMC Cancer, December 2014
DOI 10.1186/1471-2407-14-964
Pubmed ID
Authors

Yuji Miura, Chiyo K Imamura, Koya Fukunaga, Yoshihiko Katsuyama, Koichi Suyama, Toshikazu Okaneya, Taisei Mushiroda, Yuichi Ando, Toshimi Takano, Yusuke Tanigawara

Abstract

Sunitinib is a multi-targeted receptor tyrosine kinase inhibitor that acts against receptors for vascular endothelial growth factor and platelet-derived growth factor. Common toxicities of sunitinib treatment include hypertension, hand-foot syndrome, vomiting, and diarrhea, and the proportion of grade 3 or 4 adverse events relating to sunitinib treatment range from 1 to 13% for all categories. It is reported that increased exposure to sunitinib is associated with improved clinical outcomes but also carries an increased risk of adverse effects.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 45 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 16%
Student > Master 7 16%
Student > Ph. D. Student 3 7%
Student > Doctoral Student 3 7%
Professor 2 4%
Other 10 22%
Unknown 13 29%
Readers by discipline Count As %
Medicine and Dentistry 8 18%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Biochemistry, Genetics and Molecular Biology 3 7%
Agricultural and Biological Sciences 3 7%
Nursing and Health Professions 3 7%
Other 9 20%
Unknown 16 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2014.
All research outputs
#20,706,566
of 23,306,612 outputs
Outputs from BMC Cancer
#6,593
of 8,440 outputs
Outputs of similar age
#299,995
of 357,186 outputs
Outputs of similar age from BMC Cancer
#133
of 159 outputs
Altmetric has tracked 23,306,612 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,440 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 357,186 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 159 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.