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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The survival outcomes and prognosis of stage IV non-small-cell lung cancer treated with thoracic three-dimensional radiotherapy combined with chemotherapy
|
|---|---|
| Published in |
Radiation Oncology, December 2014
|
| DOI | 10.1186/s13014-014-0290-7 |
| Pubmed ID | |
| Authors |
ShengFa Su, YinXiang Hu, WeiWei Ouyang, Zhu Ma, Bing Lu, QingSong Li, HuiQin Li, ZhiYong Wang, Yu Wang |
| Abstract |
BackgroundThe impact of thoracic three-dimensional radiotherapy on the prognosis for stage IV non-small-cell lung cancer is unclear. This study is to investigate survival outcomes and prognosis in patients with stage IV non-small cell lung cancer (NSCLC) treated with thoracic three-dimensional radiotherapy and systemic chemotherapy.MethodsNinety three patients with stage IV NSCLC had received at least four cycles of chemotherapy and thoracic three-dimensional radiotherapy of ¿40 Gy on primary tumors. The data from these patients were retrospectively analyzed.ResultsOf the 93 patients, the median survival time (MST) was 14.0 months, and the 1, 2, and 3-year survival rates were 54.8%, 20.4%, and 12.9%, respectively. The MST of patients received radiation dose to primary tumor ¿63Gy and <63 Gy for primary tumor were 15.0 and 8.0 months, respectively (P¿=¿0.001). Patients had metastasis to a single site and lower tumor volume (<170 cm3) also produced longer overall survival time (P¿=¿0.002, P¿=¿0.020, respectively). For patients with metastasis at a single site, thoracic radiation dose ¿63 Gy remained a prognostic factor for better overall survival (P¿=¿0.030); patients with metastases at multiple sites, radiation dose ¿63 Gy had a trend to improve overall survival (P¿=¿0.062). A multivariate analysis showed that radiation dose ¿63 Gy (P¿=¿0.017) and metastasis to a single site (P¿=¿0.038) are associated with better overall survival, and the volume of primary tumor was marginally correlated with OS (P¿=¿0.054).ConclusionsIn combination with systemic chemotherapy, radiation dose ¿63 Gy on primary tumor and metastasis to a single site are significant factors for better OS, aggressive thoracic radiotherapy may have an important role in improving OS. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 12 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 3 | 25% |
| Student > Master | 2 | 17% |
| Student > Doctoral Student | 1 | 8% |
| Unknown | 6 | 50% |
| Readers by discipline | Count | As % |
|---|---|---|
| Nursing and Health Professions | 2 | 17% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 8% |
| Biochemistry, Genetics and Molecular Biology | 1 | 8% |
| Medicine and Dentistry | 1 | 8% |
| Unknown | 7 | 58% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 December 2014.
All research outputs
#13,185,276
of 22,774,233 outputs
Outputs from Radiation Oncology
#597
of 2,050 outputs
Outputs of similar age
#169,184
of 353,309 outputs
Outputs of similar age from Radiation Oncology
#20
of 91 outputs
Altmetric has tracked 22,774,233 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,050 research outputs from this source. They receive a mean Attention Score of 2.7. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,309 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 91 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.