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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice
|
|---|---|
| Published in |
Molecular Neurodegeneration, December 2014
|
| DOI | 10.1186/1750-1326-9-58 |
| Pubmed ID | |
| Authors |
Michael D Boska, Prasanta K Dash, Jaclyn Knibbe, Adrian A Epstein, Sidra P Akhter, Natasha Fields, Robin High, Edward Makarov, Stephen Bonasera, Harris A Gelbard, Larisa Y Poluektova, Howard E Gendelman, Santhi Gorantla |
| Abstract |
Host-species specificity of the human immunodeficiency virus (HIV) limits pathobiologic, diagnostic and therapeutic research investigations to humans and non-human primates. The emergence of humanized mice as a model for viral infection of the nervous system has overcome such restrictions enabling research for HIV-associated end organ disease including behavioral, cognitive and neuropathologic deficits reflective of neuroAIDS. Chronic HIV-1 infection of NOD/scid-IL-2Rgcnull mice transplanted with human CD34+ hematopoietic stem cells (CD34-NSG) leads to persistent viremia, profound CD4+ T lymphocyte loss and infection of human monocyte-macrophages in the meninges and perivascular spaces. Murine cells are not infected with virus. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Venezuela, Bolivarian Republic of | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 60 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 27% |
| Student > Master | 11 | 18% |
| Student > Doctoral Student | 7 | 12% |
| Student > Bachelor | 5 | 8% |
| Researcher | 3 | 5% |
| Other | 4 | 7% |
| Unknown | 14 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 20% |
| Agricultural and Biological Sciences | 6 | 10% |
| Neuroscience | 6 | 10% |
| Nursing and Health Professions | 4 | 7% |
| Psychology | 4 | 7% |
| Other | 14 | 23% |
| Unknown | 14 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2015.
All research outputs
#18,387,239
of 22,775,504 outputs
Outputs from Molecular Neurodegeneration
#784
of 847 outputs
Outputs of similar age
#255,986
of 353,309 outputs
Outputs of similar age from Molecular Neurodegeneration
#20
of 20 outputs
Altmetric has tracked 22,775,504 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 847 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,309 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.