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Calculation of the disease burden associated with environmental chemical exposures: application of toxicological information in health economic estimation

Overview of attention for article published in Environmental Health, December 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

news
9 news outlets
blogs
3 blogs
policy
4 policy sources
twitter
63 X users
facebook
6 Facebook pages
googleplus
2 Google+ users

Citations

dimensions_citation
78 Dimensions

Readers on

mendeley
237 Mendeley
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Title
Calculation of the disease burden associated with environmental chemical exposures: application of toxicological information in health economic estimation
Published in
Environmental Health, December 2017
DOI 10.1186/s12940-017-0340-3
Pubmed ID
Authors

Philippe Grandjean, Martine Bellanger

Abstract

Calculation of costs and the Burden of Disease (BoD) is useful in developing resource allocation and prioritization strategies in public and environmental health. While useful, the Disability-Adjusted Life Year (DALY) metric disregards subclinical dysfunctions, adheres to stringent causal criteria, and is hampered by gaps in environmental exposure data, especially from industrializing countries. For these reasons, a recently calculated environmental BoD of 5.18% of the total DALYs is likely underestimated. We combined and extended cost calculations for exposures to environmental chemicals, including neurotoxicants, air pollution, and endocrine disrupting chemicals, where sufficient data were available to determine dose-dependent adverse effects. Environmental exposure information allowed cost estimates for the U.S. and the EU, for OECD countries, though less comprehensive for industrializing countries. As a complement to these health economic estimations, we used attributable risk valuations from expert elicitations to as a third approach to assessing the environmental BoD. For comparison of the different estimates, we used country-specific monetary values of each DALY. The main limitation of DALY calculations is that they are available for few environmental chemicals and primarily based on mortality and impact and duration of clinical morbidity, while less serious conditions are mostly disregarded. Our economic estimates based on available exposure information and dose-response data on environmental risk factors need to be seen in conjunction with other assessments of the total cost for these environmental risk factors, as our estimate overlaps only slightly with the previously estimated environmental DALY costs and crude calculations relying on attributable risks for environmental risk factors. The three approaches complement one another and suggest that environmental chemical exposures contribute costs that may exceed 10% of the global domestic product and that current DALY calculations substantially underestimate the economic costs associated with preventable environmental risk factors. By including toxicological and epidemiological information and data on exposure distributions, more representative results can be obtained from utilizing health economic analyses of the adverse effects associated with environmental chemicals.

X Demographics

X Demographics

The data shown below were collected from the profiles of 63 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 237 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 237 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 42 18%
Student > Master 28 12%
Other 20 8%
Student > Ph. D. Student 20 8%
Student > Doctoral Student 13 5%
Other 45 19%
Unknown 69 29%
Readers by discipline Count As %
Environmental Science 33 14%
Agricultural and Biological Sciences 24 10%
Medicine and Dentistry 20 8%
Nursing and Health Professions 17 7%
Pharmacology, Toxicology and Pharmaceutical Science 11 5%
Other 48 20%
Unknown 84 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 146. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2024.
All research outputs
#293,186
of 26,052,823 outputs
Outputs from Environmental Health
#91
of 1,621 outputs
Outputs of similar age
#6,293
of 450,943 outputs
Outputs of similar age from Environmental Health
#4
of 35 outputs
Altmetric has tracked 26,052,823 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,621 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 38.1. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 450,943 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.