Title |
Tourette syndrome and other neurodevelopmental disorders: a comprehensive review
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Published in |
Child and Adolescent Psychiatry and Mental Health, December 2017
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DOI | 10.1186/s13034-017-0196-x |
Pubmed ID | |
Authors |
Elena Cravedi, Emmanuelle Deniau, Marianna Giannitelli, Jean Xavier, Andreas Hartmann, David Cohen |
Abstract |
Gilles de la Tourette syndrome (TS) is a complex developmental neuropsychiatric condition in which motor manifestations are often accompanied by comorbid conditions that impact the patient's quality of life. In the DSM-5, TS belongs to the "neurodevelopmental disorders" group, together with other neurodevelopmental conditions, frequently co-occurring. In this study, we searched the PubMed database using a combination of keywords associating TS and all neurodevelopmental diagnoses. From 1009 original reports, we identified 36 studies addressing TS and neurodevelopmental comorbidities. The available evidence suggests the following: (1) neurodevelopmental comorbidities in TS are the rule, rather than the exception; (2) attention deficit/hyperactivity disorder (ADHD) is the most frequent; (3) there is a continuum from a simple (TS + ADHD or/and learning disorder) to a more complex phenotype (TS + autism spectrum disorder). We conclude that a prompt diagnosis and a detailed description of TS comorbidities are necessary not only to understand the aetiological basis of neurodevelopmental disorders but also to address specific rehabilitative and therapeutic approaches. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 29% |
Finland | 1 | 14% |
Canada | 1 | 14% |
United States | 1 | 14% |
Unknown | 2 | 29% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 86% |
Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 121 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 17 | 14% |
Researcher | 16 | 13% |
Student > Ph. D. Student | 15 | 12% |
Student > Master | 14 | 12% |
Other | 6 | 5% |
Other | 18 | 15% |
Unknown | 35 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 24 | 20% |
Medicine and Dentistry | 15 | 12% |
Neuroscience | 13 | 11% |
Biochemistry, Genetics and Molecular Biology | 5 | 4% |
Nursing and Health Professions | 4 | 3% |
Other | 17 | 14% |
Unknown | 43 | 36% |