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Total arsenic and speciation analysis of saliva and urine samples from individuals living in a chronic arsenicosis area in China

Overview of attention for article published in Environmental Health and Preventive Medicine, May 2017
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (64th percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

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Title
Total arsenic and speciation analysis of saliva and urine samples from individuals living in a chronic arsenicosis area in China
Published in
Environmental Health and Preventive Medicine, May 2017
DOI 10.1186/s12199-017-0652-5
Pubmed ID
Authors

Dapeng Wang, Yasuyo Shimoda, Sanxiang Wang, Zhenghui Wang, Jian Liu, Xing Liu, Huanyu Jin, Fenfang Gao, Jian Tong, Kenzo Yamanaka, Jie Zhang, Yan An

Abstract

It is generally acknowledged that the determination of harmful chemical compounds excreted into saliva is useful for assessing their exposure levels. The aim of the present study was to compare the total arsenic and its species in saliva and urine samples collected from the people residing in an arsenic-contaminated area of China and to further verify the feasibility of using salivary arsenic as a new biomarker of arsenic exposure. Total arsenic and speciation analyses in urine and saliva samples among 70 residents exposed to arsenic from drinking water in Shanxi, China were carried out by high-performance liquid chromatography-inductively coupled plasma-mass spectrometry (HPLC-ICP/MS). The result showed that, total arsenic concentration in saliva was relatively lower than in urine samples, but it existed a strong positive correlation with total urinary arsenic, drinking water arsenic and different skin lesions. For arsenic metabolism analyses, AsIII, AsV, MMA, and DMA were detected in all of the urine samples with the dominating species of DMA (73.2%). Different with urinary arsenic species, most arsenic species in saliva were not methylated. The major species in saliva was iAs (AsIII + AsV, 76.18%), followed by DMA (13.08%) and MMA (9.13%). And the primary methylation index (PMI), second methylation index (SMI) and proportion of the four different species (AsIII, AsV, MMA, and DMA) in saliva showed no significant positive relationship with that of in urine. These findings indicated saliva may be used as a useful tool for biological monitoring of total arsenic exposure in the crowd rather than an efficient tool for assessing arsenic metabolism in human body after exposed to arsenic.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 55 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 11%
Researcher 5 9%
Student > Doctoral Student 4 7%
Professor 4 7%
Student > Ph. D. Student 4 7%
Other 7 13%
Unknown 25 45%
Readers by discipline Count As %
Medicine and Dentistry 5 9%
Chemistry 4 7%
Biochemistry, Genetics and Molecular Biology 3 5%
Environmental Science 2 4%
Agricultural and Biological Sciences 2 4%
Other 10 18%
Unknown 29 53%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 October 2023.
All research outputs
#7,699,568
of 25,223,158 outputs
Outputs from Environmental Health and Preventive Medicine
#183
of 538 outputs
Outputs of similar age
#110,840
of 316,833 outputs
Outputs of similar age from Environmental Health and Preventive Medicine
#7
of 22 outputs
Altmetric has tracked 25,223,158 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 538 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.4. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,833 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.