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Non-sedation versus sedation with a daily wake-up trial in critically ill patients receiving mechanical ventilation (NONSEDA Trial): study protocol for a randomised controlled trial

Overview of attention for article published in Trials, December 2014
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Title
Non-sedation versus sedation with a daily wake-up trial in critically ill patients receiving mechanical ventilation (NONSEDA Trial): study protocol for a randomised controlled trial
Published in
Trials, December 2014
DOI 10.1186/1745-6215-15-499
Pubmed ID
Authors

Palle Toft, Hanne Tanghus Olsen, Helene Korvenius Jørgensen, Thomas Strøm, Helle Lykkeskov Nibro, Jacob Oxlund, Karl-Andre Wian, Lars Marius Ytrebø, Bjørn Anders Kroken, Michelle Chew

Abstract

Through many years, the standard care has been to use continuous sedation of critically ill patients during mechanical ventilation. However, preliminary randomised clinical trials indicate that it is beneficial to reduce the sedation level. No randomised trial has been conducted comparing sedation with no sedation, a priori powered to have all-cause mortality as primary outcome.The objective is to assess the benefits and harms of non-sedation versus sedation with a daily wake-up trial in critically ill patients.

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The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 128 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 127 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 14%
Student > Master 17 13%
Student > Ph. D. Student 14 11%
Student > Bachelor 13 10%
Other 8 6%
Other 26 20%
Unknown 32 25%
Readers by discipline Count As %
Medicine and Dentistry 51 40%
Nursing and Health Professions 22 17%
Psychology 4 3%
Agricultural and Biological Sciences 2 2%
Computer Science 2 2%
Other 11 9%
Unknown 36 28%