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Characterization of a modified ROCK2 protein that allows use of N6-ATP analogs for the identification of novel substrates

Overview of attention for article published in BMC Biotechnology, January 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

news
1 news outlet

Citations

dimensions_citation
12 Dimensions

Readers on

mendeley
8 Mendeley
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Title
Characterization of a modified ROCK2 protein that allows use of N6-ATP analogs for the identification of novel substrates
Published in
BMC Biotechnology, January 2014
DOI 10.1186/1472-6750-14-2
Pubmed ID
Authors

Amber L Couzens, R Montgomery Gill, Michael P Scheid

Abstract

The Rho-associated coiled-coil kinase-2 (ROCK2) is an important signaling transducer in the transmission of extracellular signals effecting organization of the actin cytoskeleton. ROCK2 has been implicated in numerous pathologies and the current focus is on understanding the molecular events that couple ROCK2 activity to biological function. To aid in the search for new ROCK2 substrates, we have developed an analog-sensitive (AS) ROCK2 protein that allows the use of selective ATP analogs that are not efficiently utilized by other protein kinases.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 25%
Student > Ph. D. Student 1 13%
Professor 1 13%
Student > Master 1 13%
Professor > Associate Professor 1 13%
Other 0 0%
Unknown 2 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 38%
Agricultural and Biological Sciences 1 13%
Chemistry 1 13%
Medicine and Dentistry 1 13%
Unknown 2 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 December 2014.
All research outputs
#4,399,028
of 22,775,504 outputs
Outputs from BMC Biotechnology
#213
of 935 outputs
Outputs of similar age
#49,928
of 304,918 outputs
Outputs of similar age from BMC Biotechnology
#2
of 15 outputs
Altmetric has tracked 22,775,504 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 935 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 304,918 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.