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Deregulation of microRNAs Let-7a and miR-21 mediate aberrant STAT3 signaling during human papillomavirus-induced cervical carcinogenesis: role of E6 oncoprotein

Overview of attention for article published in BMC Cancer, December 2014
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Title
Deregulation of microRNAs Let-7a and miR-21 mediate aberrant STAT3 signaling during human papillomavirus-induced cervical carcinogenesis: role of E6 oncoprotein
Published in
BMC Cancer, December 2014
DOI 10.1186/1471-2407-14-996
Pubmed ID
Authors

Gauri Shishodia, Gaurav Verma, Yogesh Srivastava, Ravi Mehrotra, Bhudev Chandra Das, Alok Chandra Bharti

Abstract

Aberrantly expressed and constitutively active STAT3 signaling plays a pivotal role in initiation and progression of human papillomavirus-induced cervical carcinogenesis. However, the underlying mechanism(s) responsible for pleiotropic effects of STAT3 signaling is poorly understood. In view of emerging regulatory role of microRNAs, Let-7a and miR-21 that may interact with STAT3 signaling and/or its downstream effectors, present study was designed in HPV16-positive cervical cancer cells to assess the functional contribution of these miRs in STAT3 signaling in cervical cancer.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 50 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 16%
Researcher 7 14%
Student > Doctoral Student 5 10%
Student > Bachelor 5 10%
Student > Master 5 10%
Other 8 16%
Unknown 12 24%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 15 30%
Agricultural and Biological Sciences 9 18%
Medicine and Dentistry 7 14%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Chemistry 2 4%
Other 2 4%
Unknown 13 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2015.
All research outputs
#18,387,239
of 22,775,504 outputs
Outputs from BMC Cancer
#5,418
of 8,286 outputs
Outputs of similar age
#255,548
of 352,836 outputs
Outputs of similar age from BMC Cancer
#99
of 147 outputs
Altmetric has tracked 22,775,504 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,286 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,836 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 147 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.