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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Loss of non-coding RNA expression from the DLK1-DIO3 imprinted locus correlates with reduced neural differentiation potential in human embryonic stem cell lines
|
|---|---|
| Published in |
Stem Cell Research & Therapy, January 2015
|
| DOI | 10.1186/scrt535 |
| Pubmed ID | |
| Authors |
Chu-Fan Mo, Fang-Chun Wu, Kang-Yu Tai, Wei-Chun Chang, Kai-Wei Chang, Hung-Chih Kuo, Hong-Nerng Ho, Hsin-Fu Chen, Shau-Ping Lin |
| Abstract |
Pluripotent stem cells are increasingly used to build therapeutic models, including the transplantation of neural progenitors derived from human embryonic stem cells (hESCs). Recently, long non-coding RNAs (lncRNAs), including delta-like homolog 1 gene and the type III iodothyronine deiodinase gene (DLK1-DIO3) imprinted locus-derived Maternally Expressed Gene 3 (MEG3), were found to be expressed during neural development. The deregulation of these lncRNAs is associated with various neurological diseases. The imprinted locus DLK1-DIO3 encodes abundant non-coding RNAs (ncRNAs) that are regulated by differential methylation of the locus. We aim to study the correlation between the DLK1-DIO3-derived ncRNAs and the capacity of hESCs to differentiate into neural lineages. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 50% |
| Scientists | 1 | 25% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 1% |
| Denmark | 1 | 1% |
| Unknown | 68 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 24% |
| Researcher | 15 | 21% |
| Student > Master | 11 | 16% |
| Student > Bachelor | 9 | 13% |
| Other | 5 | 7% |
| Other | 6 | 9% |
| Unknown | 7 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 29 | 41% |
| Biochemistry, Genetics and Molecular Biology | 16 | 23% |
| Medicine and Dentistry | 4 | 6% |
| Neuroscience | 4 | 6% |
| Nursing and Health Professions | 1 | 1% |
| Other | 8 | 11% |
| Unknown | 8 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 January 2015.
All research outputs
#13,926,802
of 22,776,824 outputs
Outputs from Stem Cell Research & Therapy
#1,028
of 2,418 outputs
Outputs of similar age
#181,202
of 352,499 outputs
Outputs of similar age from Stem Cell Research & Therapy
#18
of 21 outputs
Altmetric has tracked 22,776,824 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,418 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,499 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.