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Short- and long-term outcomes in infective endocarditis patients: a systematic review and meta-analysis

Overview of attention for article published in BMC Cardiovascular Disorders, December 2017
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Title
Short- and long-term outcomes in infective endocarditis patients: a systematic review and meta-analysis
Published in
BMC Cardiovascular Disorders, December 2017
DOI 10.1186/s12872-017-0729-5
Pubmed ID
Authors

Tadesse Melaku Abegaz, Akshaya Srikanth Bhagavathula, Eyob Alemayehu Gebreyohannes, Alemayehu B. Mekonnen, Tamrat Befekadu Abebe

Abstract

Despite advances in medical knowledge, technology and antimicrobial therapy, infective endocarditis (IE) is still associated with devastating outcomes. No reviews have yet assessed the outcomes of IE patients undergoing short- and long-term outcome evaluation, such as all-cause mortality and IE-related complications. We conducted a systematic review and meta-analysis to examine the short- and long-term mortality, as well as IE-related complications in patients with definite IE. A computerized systematic literature search was carried out in PubMed, Scopus and Google Scholar from 2000 to August, 2016. Included studies were published studies in English that assessed short-and long-term mortality for adult IE patients. Pooled estimations with 95% confidence interval (CI) were calculated with DerSimonian-Laird (DL) random-effects model. Sensitivity and subgroup analyses were also performed. Publication bias was evaluated using inspection of funnel plots and statistical tests. Twenty five observational studies (retrospective, 14; prospective, 11) including 22,382 patients were identified. The overall pooled mortality estimates for IE patients who underwent short- and long-term follow-up were 20% (95% CI: 18.0-23.0, P < 0.01) and 37% (95% CI: 27.0-48.0, P < 0.01), respectively. The pooled prevalence of cardiac complications in patients with IE was found to be 39% (95%CI: 32.0-46.0) while septic embolism and renal complications accounted for 25% (95% CI: 20.0-31) and 19% (95% CI: 14.0-25.0) (all P < 0.01), respectively. Irrespective of the follow-up period, a significantly higher mortality rate was reported in IE patients, and the burden of IE-related complications were immense. Further research is needed to assess the determinants of overall mortality in IE patients, as well as well-designed observational studies to conform our results.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 127 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 127 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 17 13%
Other 14 11%
Student > Ph. D. Student 12 9%
Student > Master 10 8%
Student > Postgraduate 9 7%
Other 23 18%
Unknown 42 33%
Readers by discipline Count As %
Medicine and Dentistry 53 42%
Nursing and Health Professions 4 3%
Agricultural and Biological Sciences 4 3%
Unspecified 4 3%
Psychology 2 2%
Other 11 9%
Unknown 49 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 December 2022.
All research outputs
#15,164,620
of 23,322,966 outputs
Outputs from BMC Cardiovascular Disorders
#772
of 1,676 outputs
Outputs of similar age
#254,502
of 440,860 outputs
Outputs of similar age from BMC Cardiovascular Disorders
#5
of 12 outputs
Altmetric has tracked 23,322,966 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,676 research outputs from this source. They receive a mean Attention Score of 3.9. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 440,860 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.